Src Activation Helps Regulate Capacitation and Acrosome Reaction

April 2009
Fertility Weekly;4/13/2009, p8
Academic Journal
The article reports on the study conducted by G. Varano and associates which examines the role of Src kinase in sperm activation in Italy. Phosphorylated tyrosines identify the active and active form of Src kinase during the main process of activation and reveal significant increase in phosphorylation in Tyr416. It concludes that the presence, localization and functional activity of Src isoform triggers capacitation and acrosome reaction in human sperm.


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