The Separation of Enantiomers on Modified Cyclodextrins by Capillary Electrochromatography (CEC)

Wistuba, Dorothee; Schurig, Volker
February 2009
LC-GC Europe;Feb2009, Vol. 22 Issue 2, p60
Trade Publication
Various modes of capillary electrochromatography (CEC) for the separation of enantiomers on immobilized cyclodextrin derivatives are described. The following techniques have been used: (i) open-tubular electrochromatography (o-CEC), (ii) packed electrochromatography (p-CEC) and (iii) monolithic electrochromatography (rod-CEC). Three different strategies to prepare enantioselective cyclodextrin-coated chiral monoliths are described. The advantages and disadvantages of the various methods are outlined.


Related Articles

  • Light-Guiding Fused-Silica Capillary Tubing. Macomber, Joe; Nelson, Gary // LC-GC North America;02/01/2002 Supplement, Vol. 20 Issue 2, p35 

    Focuses on the use of light-guiding fused-silica capillary tubing for chromatographic analysis. Background on the use of synthetic fused-silica capillary tubing in the separation sciences; Features of the capillary tubing; Advantage of using the capillary tubing.

  • Miniaturized liquid separation techniques in bioanalysis. Holland, Lisa A.; McKeon, Jocelyn // Analytical & Bioanalytical Chemistry;Jan2004, Vol. 378 Issue 1, p40 

    The article focuses on liquid separation techniques in bioanalysis. The list of biologically relevant analytes is diverse: biopolymers like DNA, RNA, protein, carbohydrate, biomonomers: amino acids, nucleic acids, monosaccharides, lipids, and other molecules. The drive for core information in...

  • CALENDAR.  // LC-GC Europe;Dec2003, Vol. 16 Issue 12, p838 

    Lists conferences on separation science for February to June 2004. Eighth International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers in Brudges, Belgium; Environmental Mass Spectrometry Meeting in Chester, England; 27th International Symposium on...

  • Developing High-Throughput Separations in Capillary GC.  // LC-GC North America;Mar2012, Vol. 30 Issue 3, p274 

    The article discusses how to produce high-throughput separations in capillary gas chromatography (GC). It notes that several other important instruments should be put into consideration when moving to fast capillary GC methods such as rapid introduction of sample for the inlet, reducing system...

  • Separation of Ionic Analytes using Supercritical Fluid Chromatography. Taylor, Larry T. // LC-GC North America;Sep2009 Application Notebook, Vol. 27, p62 

    Supercritical fluid chromatography (SFC) has been practiced for approximately 50 years. SFC on packed columns for both qualitative and quantitative purposes underwent a renaissance in interest at the beginning of the 1990s when limitations of capillary SFC became obvious and important progress...

  • The use of etched, chemically modified, rectangular capillaries as a separation medium for open tubular capillary electrochromatography. Pesek, Joseph J.; Matyska, Maria T.; Freeman, Kelley; Carlon, Gabriella // Analytical & Bioanalytical Chemistry;Jun2005, Vol. 382 Issue 3, p795 

    The use of etched, chemically modified, capillaries with a rectangular inner channel for open tubular electrochromatography is investigated. Comparisons of separation capabilities are made between circular and rectangular capillaries undergoing the same etching and chemical modification...

  • Polyimide Coated Capillary Tubing: Internal Pressure Capabilities. Macomber, Joe; Forest, Craig R. // LC-GC North America;Sep2006 Supplement, Vol. 24, p67 

    The article discusses the internal pressure handling capabilities and strength and the related consideration of fused capillary tubing from a theoretical standpoint. As the use of fused capillary tubing proved to be a popular column support in liquid chromatography, comes the need for high...

  • Capillary-channeled polymer (C-CP) fibers as a stationary phase in microbore high-performance liquid chromatography columns. Stanelle, Rayman D.; Mignanelli, Massimiliano; Brown, Phil; Marcus, R. Kenneth // Analytical & Bioanalytical Chemistry;Dec2005, Vol. 384 Issue 1, p250 

    Microbore columns utilizing polypropylene capillary-channeled polymer (C-CP) fibers as the stationary phase in high-performance liquid chromatography (HPLC) have been investigated. The polypropylene C-CP fiber diameter is ∼50 μm, with eight channels along the periphery of the fiber...

  • Extracolumn Effects. Dolan, John W. // LC-GC Europe;Mar2005, Vol. 18 Issue 3, p130 

    The article focuses on the impact of plumbing on column performance. The article author views that when real samples are analyzed on typical liquid chromatographic systems, rarely do we observe plate numbers anywhere near the manufacturer's claim. Some of this performance degradation is a result...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics