The facilitator in acute kidney injury: TWEAK

Sanz, A. B.; Sánchez Sánchez-Nino, M. D.; Izquierdo, M. C.; Moreno, J. A.; Ucero, A. C.; Benito-Martín, A.; Santamaría, B.; Burgos, C.; Egido, J.; Ramos, A.; Berzal, S.; Coto, E.; Ruiz-Ortega, M.; Blanco-Colio, L. M.; Ortiz, A.
December 2008
Nefrologia;Dec2008, Vol. 28 Issue 6, p587
Academic Journal
The article presents information on acute kidney injury (AKI). It is informed that acute and chronic failure of renal function is characterized by loss of renal tubular cells. Tubular cell death is believed to be the best histopathological correlate of renal dysfunction during AKI. A study is being presented which attempts to identify factors which contribute to AKI. The study involves a novel cytokine-ligand pair, Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and Fn14 gene.


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