Acute allergic interstitial nephritis after use of pantoprazole

Ricketson, Jeffrey; Kimel, Gil; Spence, James; Weir, Rene
March 2009
CMAJ: Canadian Medical Association Journal;3/4/2009 Doctor's Health Matters, Vol. 180, p535
Academic Journal
The article presents a case of a 57-year-old man presented to a hospital after suffering from progressive malaise, fever, myalgia, vomiting, polydipsia, polyuria, and diarrhea for two weeks. It states that the man had a history of gastroesophageal reflux and did not respond to ranitidines instead took 40 mg oral pantoprazole six weeks earlier. It mentions that the patient also had a mild hyperkalemia but with a normal level of electrolyte levels. It notes that the man was diagnosed with allergic interstitial nephritis which is most likely caused by using pantoprazole. Furthermore, occasional use of ibuprofen is also considered as potential cause of the acute interstitial nephritis.


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