Different Ankle Brachial Index Levels in Asymptomatic Hemodialysis Patients

Gelev, Saso; Spasovski, Goce; Dzikova, Sonja; Tosev, Slavcho; Bosevski, Marjan; Selim, Gjulsen; Dzekova, Pavlina; Asani, Arben; Amitov, Vili; Sikole, Aleksandar
September 2008
Macedonian Journal of Medical Sciences;9/15/2008, Vol. 1 Issue 1, p44
Academic Journal
Resting ankle brachial systolic pressure index (ABI) level of 0.90 is 95% sensitive in detecting angiogram-positive peripheral arterial disease (PAD) and that falsely elevated pressures or incompressible arteries at the ankle level and ABI > 1.30 is caused by mediosclerosis. We evaluated 94 hemodialysis (HD) patients for the presence of PAD and mediosclerosis using ABI measurement, and the presence of atherosclerotic lesions using high resolution B-mode ultrasonography of the common carotid (CCA) and femoral arteries (FA). Asymptomatic HD patients with high ABI (mediosclerosis) and low ABI (PAD) levels were common. Patients with normal and high ABI levels had high percentage of atherosclerotic lesions. Older age, diabetes and low serum albumin, and higher doses of prescribed calcium carbonate were associated (p<0.05) with low levels of ABI in our HD patients. Male gender, higher blood pressure and presence of diabetes were associated (p<0.05) with high ABI levels. Low and high ABI levels were not associated with the specific risks such as elevated serum phosphate, calcium phosphate product and intact parathyroid hormone levels. Arterial disease in asymptomatic HD patients is frequent. Screening for atherosclerotic lesions in HD patients should be recommended even if they had no symptoms.


Related Articles

  • Carotid Intima-Media Thickness as a Marker of Atherosclerosis in Hemodialysis Patients. Farahani, Maryam Moshkani // Iranian Journal of Kidney Diseases;May2012, Vol. 6 Issue 3, p161 

    The author reflects on the role of the carotid intima-media thickness (CIMT) as a marker for evaluating the progression of atherosclerosis in hemodialysis patients. He cites a study, which examines the relationship between the maximum and the mean CIMT in hemodialysis patients with different...

  • Significance of the Intima-Media Thickness of Carotid and Thoracic Aorta in Coronary Artery Disease in the South Indian Population. Meenakshisundaram, Ramachandran; Devidutta, Soumen; Michaels, Andrew D.; Senthilkumaran, Subramanian; Rajendiran, Chinnasamy; Thirumalaikolundusubramanian, Ponniah // Heart Views;Oct-Dec2011, Vol. 12 Issue 4, p150 

    Background: Ultrasound detected intima-media thickness (IMT) of the carotid artery and thoracic aorta are possible screening tests to assess the risk of coronary artery disease (CAD) in asymptomatic individuals. Objective: Aim of the study was to assess the utility of carotid and aortic IMT as a...

  • The correlation between the severity of peripheral arterial disease and carotid occlusive disease. Long, T.H.; Criqui, M.H.; O Denenberg, J.; Vasilevskis, E.E.; Klauber, M.R.; Fronek, A. // Vascular Medicine;1999, Vol. 4 Issue 3, p135 

    Peripheral arterial disease (PAD) and carotid occlusive disease (COD) are both known to be specific manifestations of atherosclerosis. Because they both have a common cause, it is reasonable to hypothesize that they should correlate with each other to a certain extent, and previous studies have...

  • The antihyperlipidemic pravastatin slows the rate of carotid-wall thickening.  // Modern Medicine;Jun95, Vol. 63 Issue 6, p48 

    Presents an abstract on the article `Pravastatin, Lipids, and Atherosclerosis in the Carotid Arteries,' by J.R. Crouse III, R.P. Byington, et al., which was published in the `American Journal of Cardiology' dated March 1, 1995.

  • USEFULNESS OF STRAIN MEASUREMENT IN THE ASSESSMENT OF CAROTID ARTERIES STIFFNESS IN TYPE 1 DIABETES PATIENTS. Podgórski, M. T.; Szymańska-Garbacz, E.; Grzelak, P.; Stefańczyk, L.; Loba, J.; Czupryniak, L. // Acta Endocrinologica (1841-0987);2015, Vol. 11 Issue 4, p470 

    Context. Increased arterial stiffness is an independent risk factor of cardiovascular events in patients with diabetes mellitus (DM). Objective. We aimed to evaluate elastic properties of common carotid arteries (CCA) in patients with DM type 1 (T1DM) by means of ultrasonographically based...

  • Independent association between serum sclerostin levels and carotid artery atherosclerosis in prevalent haemodialysis patients. Kirkpantur, Alper; Balci, Mustafa; Turkvatan, Aysel; Afsar, Baris // Clinical Kidney Journal;Dec2015, Vol. 8 Issue 6, p737 

    Background: Sclerostin is a soluble inhibitor of theWntsignalling pathway and has been shownto be associated with decreased bone turnover and vascular and/or valvular calcification in patients with chronic kidney disease. Common carotid artery intima-media thickness (CIMT) assessment and common...

  • Carotid artery thickness in children and young adults with end stage renal disease. Poyrazoglu, Hakan M.; D�s�nsel, Ruhan; Yikilmaz, Ali; Narin, Nazmi; Anarat, Ruksan; G�nd�z, Z�beyde; Coskun, Abdulhakim; Baykan, Ali; �zt�rk, Ahmet // Pediatric Nephrology;Jan2007, Vol. 22 Issue 1, p109 

    Atherosclerosis is a major cause of morbidity and mortality for ESRD patients and we have little knowledge about the presence and risk factors of atherosclerosis in children with CRF. The measurement of carotid artery intima-media thickness (cIMT) using high-resolution ultrasonography is...

  • Reliability of a freehand three-dimensional ultrasonic device allowing anatomical orientation "at a glance": Study protocol for 3D measurements with Curefab CS. Feurer, Regina; Hennersperger, C.; Runyan, J. B.; Seifert, C. L.; Pongratz, J.; Wilhelm, M.; Pelisek, J.; Navab, N.; Bartels, E.; Poppert, H. // Journal of Biomedical Graphics & Computing;Dec2012, Vol. 2 Issue 2, p1 

    Background and Purpose: 3D ultrasonic measurement of carotid atherosclerotic lesions has emerged as an important tool for research and patient management. We sought to evaluate the accuracy and the reliability of a new easy-to-use magnetically tracked freehand 3D ultrasonic device with quick...

  • A hybrid framework for registration of carotid ultrasound images combining iconic and geometric features. Gupta, Anupama; Verma, Harsh; Gupta, Savita // Medical & Biological Engineering & Computing;Sep2013, Vol. 51 Issue 9, p1043 

    Stroke is the third major cause of death worldwide behind heart disease and cancer. Carotid atherosclerosis is the most frequent cause of ischemic stroke. Early diagnosis of carotid plaque and serial monitoring of its size with the help of imaging modalities can help to prevent the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics