Genetic Architecture of Adiposity and Organ Weight Using Combined Generation QTL Analysis
- Gene makes some people fatter. // New Scientist;4/21/2007, Vol. 194 Issue 2600, p16
The article focuses on how an altered version of the FTO gene may increase the risk of obesity.
- Newest fat gene. // Joe Weider's Muscle & Fitness;Feb96, Vol. 57 Issue 2, p33
Reports on the discovery of a fat gene by researchers at the Johns Hopkins Medical Centers. Involvement of the beta-3 adrenergic receptor; Possible member of a group of factors producing the genetic component of obesity.
- Obesity genes: so close and yet so far... // Journal of Biology;2008, Vol. 7, p93
Little is known about genetic variants that predispose individuals toward leanness or fatness. This minireview highlights recent advances in the study of human populations, animal models and synergistic efforts as described by De Luca and colleagues in BMC Genetics, which are beginning to...
- A Functional Variant of NEDD4L Is Associated with Obesity and Related Phenotypes in a Han Population of Southern China. Yu-Lin Wang; Hui-Ying Liang; Yun-He Gao; Xue-Ji Wu; Xi Chen; Bing-Ying Pan; Xue-Xi Yang; Hua-Zhang Liu // International Journal of Molecular Sciences;Apr2013, Vol. 14 Issue 4, p7433
NEDD4L is a candidate gene for hypertension, both functionally and genetically. Recently, studies showed evidence for the association of NEDD4L with obesity, a key intermediate phenotype in hypertension. To further investigate the relationship between NEDD4L and body mass-related phenotypes, we...
- Can genes be blamed for obesity? Cameron-Smith, David; Collier, Greg R. // Nutridate;May98, Vol. 9 Issue 2, p1
Discusses the role of genes in obesity. Health risks of obesity; Prevalence of obesity in Australia; Genes responsible for obesity. INSET: Student activities.
- Cilia May Provide Targets for Obesity and Other Diseases. Shaffer, Catherine // Drug Discovery & Development;Jun2004, Vol. 7 Issue 6, p20
Reports on the identification of a host of genes involved in the formation of cilia and flagella. Result of defects in the microtubule-based structures; Implications of cilia for many human diseases; Importance of cilia for understanding family inherited obesity.
- Obesity: Fat chance. Shadan, Sadaf // Nature;2/26/2009, Vol. 457 Issue 7233, p1095
The article discusses research on the role that the gene labeled FTO has on obesity. By studying mice that lacked the gene and then contrasting them with normal mice, researchers found that the absence of FTO did not affect embryonic development but resulted in a weight reduction attributed to a...
- Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. Mykytyn, Kirk; Braun, Terry; Carmi, Rivka; Haider, Neena B.; Searby, Charles C.; Shastri, Mythreyi; Beck, Gretel; Wright, Alan F.; Iannaccone, Alessandro; Elbedour, Khalil; Riise, Ruth; Baldi, Alfonso; Raas-Rothschild, Annick; Gorman, Susan W.; Duhl, David M.; Jacobson, Samuel G.; Casavant, Thomas; Stone, Edwin M.; Sheffield, Val C. // Nature Genetics;Jun2001, Vol. 28 Issue 2, p188
Bardet?Biedl syndrome (BBS, MIM 209900) is a heterogeneous autosomal recessive disorder characterized by obesity, pigmentary retinopathy, polydactyly, renal malformations, mental retardation, and hypogenitalism. The disorder is also associated with diabetes mellitus, hypertension, and congenital...
- Mapping obesity genes. // Healthy Weight Journal;Jan/Feb2001, Vol. 15 Issue 1, p3
Editorial. Presents an update on the efforts of researchers at Laval University in Quebec City, Quebec to identify human obesity genes and markers. Overview of findings; Discussion on the attempts to relate DNA sequence variation in specific genes to obesity phenotypes.