Step up vs step down

March 2009
Travel Medicine Advisor;Mar2009 Supplement, p2
The article compares step-up and step-down therapies as a treatment for dyspepsia. The concept of both procedures is briefly stated. A study conducted in the Netherlands showed that patients randomly treated in the step-up and step-down process achieved a 72% and 70% treatment success rate, respectively, after a 6-month period. Reportedly, both processes have the same rate of adverse effects but the step-up process was more cost-effective than its counterpart.


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