TITLE

Interaction of Human Serum Proteins with Local Anesthetic Agents

AUTHOR(S)
SAWINSKI, VINCENT J.; RAPP, GUSTAV W.
PUB. DATE
November 1963
SOURCE
Journal of Dental Research;Nov1963, Vol. 42 Issue 6, p1429
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the interaction of two human serum proteins with ester- and amide-type local anesthetics. Human serum albumin showed a stronger affinity for lidocaine and mepivacaine than for procaine and butethamine. Human serum gamma globulin showed no significant binding interaction with the four anesthetics.
ACCESSION #
36571652

 

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