TITLE

Collagenase and Periodontal Diseases: A Review

AUTHOR(S)
FULLMER, HAROLD M.
PUB. DATE
March 1971
SOURCE
Journal of Dental Research;Mar1971, Vol. 50 Issue 2, p288
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a review of the the relationship between collagenase and periodontal diseases. The author notes that collagen is the major protein destroyed by periodontal diseases because it is the predominant organic material found in bone, gingiva, and cementum. Studies have found that collagen fragments from enzymatic hydrolysis are similar to those formed from collagenase.
ACCESSION #
36553627

Tags: COLLAGENASES;  COLLAGEN;  PERIODONTAL disease;  GUMS;  CEMENTUM;  HYDROLYSIS

 

Related Articles

  • IDENTIFICATION OF A PROTEOLYTIC ENZYME OF THE PERIODONTAL POCKET. ROTH, GENEVIEVE D.; MYERIS, HUGH I. // Journal of Dental Research;Feb1952, Vol. 31 Issue 1, p18 

    The article discusses a study on the relationship between periodontal diseases and collagenase. A fluid medium was created using a combination of horse serum, rat kidneys, distilled water, and a paper point. By watching this mixture for 21 days and comparing it to a control mixture that included...

  • The Efficacy of Bacterial Collagenase for the Digestion of Gingival Tissue Collagen. MAILMAN, MARY L. // Journal of Dental Research;Apr1979, Vol. 58 Issue 4, p1424 

    The article investigates how well bacterial collagenase digests gingival tissue collagen. Experimental procedures are described and results are discussed. Among the findings was that all proline observed in the collagenase digest comes from collagen, indicating a lack of notable degradation of...

  • Human Gingival Lymphocytes. I. Methodology for the Isolation of Human Gingival Lymphocytes. MACKLER, B. F.; WITHERS, J. A.; WOODSON, D. L.; COKER, E.; HERRIN, A.; FRIEDMAN, L.; O'NEILL, P. A. // Journal of Dental Research;Oct1979, Vol. 58 Issue 10, p1946 

    Various methodologies were examined for the isolation of inflammatory cells from diseased human gingiva. The best recovery of viable gingival lymphocytes (gMNC) was achieved by a method which combined initial collagenase digestion followed by gentle teasing with an 18-gauge needle.

  • Human Gingival Collagenase in Periodontal Disease: The Release of Collagenase and the Breakdown of Endogenous Collagen in Gingival Explants. GEIGER, SELLY; HARPER, ELVIN // Journal of Dental Research;Jan1980, Vol. 59 Issue 1, p11 

    Collagen degradation in different stages of gingival inflammation was examined. Higher collagenolytic activity and nonspecific protease activity were found in the severely inflamed gingiva, as compared to mildly inflamed or healthy gingiva. This was shown by electrophoretic studies and...

  • Glutaminase Activity of Inflamed Human Free Gingiva. Blumenthal, Neil // Journal of Dental Research;Oct1975 Supplement, Vol. 54 Issue 3, pC93 

    The article discusses a study on the possibility that a glutaminase enzyme can exist in human gingiva that hydrolyzes glutamine to produce significant amounts of glutamic acid. Gingival inflammation and glutaminase activities were determined in 30 samples of gingival tissue which were separated...

  • "Collagen Adhesion" Revisited. Selvig, Knut A.; Sigurdsson, Thorarinn J.; Wikesj�, UIf M. E. // International Journal of Periodontics & Restorative Dentistry;Dec1995, Vol. 15 Issue 6, p528 

    Histologic studies of periodontal reconstructive therapies have repeatedly shown a zone of nondescript connective tissue adaptation, or collagen adhesion, to the root surface between the apical extension of the junctional epithelium and the coronal extension of identifiable regenerated cementum....

  • Healing of fenestration-type defects following treatment with guided tissue regeneration or enamel matrix proteins : An experimental study in monkeys. Sculean, A.; Donos, N.; Brecx, M.; Karring, T.; Reich, E. // Clinical Oral Investigations;Mar2000, Vol. 4 Issue 1, p50 

    The aim of the present study was to evaluate histologically in monkeys the healing in acute fenestration-type defects following treatment with guided tissue regeneration (GTR) or enamel matrix proteins (EMD). Standardized �critical size� fenestration-type defects were produced...

  • Clinical and Histologic Evaluation of Anorganic Bovine Bone Collagen with or without a Collagen Barrier. Hartman, Gary A.; Arnold, Ralph M.; Mills, Michael P.; Cochran, David L.; Mellonig, James T. // International Journal of Periodontics & Restorative Dentistry;2004, Vol. 24 Issue 2, preceding p127 

    This study evaluated an anorganic bovine-derived xenograft (Bio-Oss Collagen) in the treatment of human periodontal defects. Four patients with intrabony defects on teeth that were treatment planned for extraction were enrolled in the study. Presurgical measurements of probing depth, attachment...

  • Expression of MMP-8 and MMP-13 Genes in the Periodontal Ligament during Tooth Movement in Rats. Takahashi, I.; Nishimura, M.; Onodera, K.; Bae, J.-W.; Mitani, H.; Okazaki, M.; Sasano, Y. // Journal of Dental Research;Aug2003, Vol. 82 Issue 8, p646 

    Periodontal ligament tissue is remodeled on both the tension and compression sides of moving teeth during orthodontic tooth movement. The present study was designed to clarify the hypothesis that the expression of MMP-8 and MMP-13 mRNA is promoted during the remodeling of periodontal ligament...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics