Photoacoustic guidance of high intensity focused ultrasound with selective optical contrasts and time-reversal

Funke, Arik R.; Aubry, Jean-François; Fink, Mathias; Boccara, Albert-Claude; Bossy, Emmanuel
February 2009
Applied Physics Letters;2/2/2009, Vol. 94 Issue 5, pN.PAG
Academic Journal
The authors present a method of focusing high intensity ultrasound by time-reversing the photoacoustic response of an optically selective target in a nonselective background. The target’s photoacoustic response was isolated from the background by subtracting the photoacoustic waveforms obtained at different optical wavelengths and convolved with a continuous signal. It was found that the focus produced was comparable in quality to that obtained by delay-law beam-forming. The method holds the promise of allowing precise targeting of high intensity focused ultrasound on nonechogenic targets, in moving environments, independently of the presence of aberrating layers.


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