A Two-year Randomized Clinical Trial of Chlorhexidine Varnish on Dental Caries in Chinese Preschool Children

Du, M. Q.; Tai, B. J.; Jiang, H.; Lo, E. C. M.; Fan, M. W.; Bian, Z.
June 2006
Journal of Dental Research;Jun2006, Vol. 85 Issue 6, p557
Academic Journal
The objective of this study was to assess the effect of six-monthly professional applications of chlorhexidine varnish on the prevention of dental caries in primary molars in Chinese preschool children. In a double-blinded, randomized, placebo-controlled clinical trial, 334 children aged 4-5 years were randomly divided into two groups. Children in the test group received six-monthly applications of a 40% chlorhexidine varnish, and the control children received a placebo varnish. Caries status of the children was assessed by two calibrated examiners at baseline and after 24 months, according to criteria recommended by the World Health Organization. The two-year mean caries increments in the test and the control group children were 1.0 and 1.6 decayed, missing, or filled molar surfaces (dmfs-molar), respectively, a 37.3% reduction (t test, p = 0.036). No side-effects were found. It was concluded that six-monthly applications of chlorhexidine varnish were effective in reducing the incidence of dental caries in primary molars.


Related Articles

  • Prevention of Dental Caries in Children from Birth Through Five Years of Age: Recommendation Statement.  // American Family Physician;2/1/2015, Vol. 91 Issue 3, p190A 

    An excerpt from "Prevention of Dental Caries in Children From Birth Through Five Years of Age: Recommendation Statement," published by the U.S. Preventive Services Task Force (USPSTF), is presented.

  • Fluoride Varnish Efficacy in Preventing Early Childhood Caries. Weintraub, J. A.; Ramos-Gomez, F.; Jue, B.; Shain, S.; Hoover, C. I.; Featherstone, J. D. B.; Gansky, S. A. // Journal of Dental Research;Feb2006, Vol. 85 Issue 2, p172 

    To determine the efficacy of fluoride varnish (5% NaF, Duraphat, Colgate) added to caregiver counseling to prevent early childhood caries, we conducted a two-year randomized, dental-examiner- masked clinical trial. Initially, 376 caries-free children, from low-income Chinese or Hispanic San...

  • The whole population approach to caries prevention in general dental practice. Tickle, Martin; Milsom, Keith // British Dental Journal;11/22/2008, Vol. 205 Issue 10, p521 

    The author reflects on massive and high-risk approach of caries prevention in general dental practice. He argues on the toolkit published by the Department of Health that offers evidence-based approach for preventive dental care among children. He presents the recent incidence of dental caries...

  • Study highlights fluoridated toothpaste use in children.  // British Dental Journal;2/13/2010, Vol. 208 Issue 3, p102 

    The article focuses on the study by the researchers for the Cochrane Oral Health Group suggesting the parents should use toothpastes with fluoride with a minimum concentration of 1,000 parts per million (ppm) to prevent tooth decay in children in Great Britain. The study found out the...

  • kids' health. Mccarthy, Laura Flynn; Johnson, Kate; Cumberbatch, Jessica; Sprinkle, Nicole // Parenting;May2004, Vol. 18 Issue 4, p37 

    Provides information on children's health and safety. Facts about a child's swollen glands; Allergy relief for kids; Advantages and disadvantages of co-sleeping with a baby; Findings of a study on the benefits of eating breakfast in preventing tooth decay in children.

  • Dental Caries and Staining after Twenty-eight Months of Rinsing with Stannous Fluoride or Sodium Fluoride. LEVERETT, D. H.; MCHUGH, W. D.; JENSEN, O. E. // Journal of Dental Research;Mar1986, Vol. 65 Issue 3, p424 

    The aim of this study was to compare the effects of daily mouthrinsing with aqueous solutions of 0.05% NaF or 0.1% SnF2 on dental caries and tooth staining. The study population consisted of 437 children, aged from 12 to 15 years at baseline, residing in a non-fluoridated community. By...

  • 'Silent epidemic' threatens our children's future. McName, James // New Hampshire Business Review;10/28/2005, Vol. 27 Issue 23, p22 

    The article urges the citizens of New Hampshire to do a better job of caring for the future workforce by combating tooth decay in children. Dental disease is considered by the U.S. surgeon general as a silent epidemic in the health of children. By jeopardizing the future of children, people are...

  • ANALYSIS OF BODY COMPOSITION IN PRESCHOOL CHILDREN FROM POZNAN, POLAND. Chalcarz, W.; Merkiel, S.; Sideravičiūtė, S. // Acta Kinesiologiae Universitatis Tartuensis;2007 Supplement, Vol. 12, p67 

    An abstract of the article "Analysis of Body Consumption in Preschool Children from Poznan, Poland," by W. Chalearz, S. Merkiel and S. Sideravičiutè.

  • THE GROWN-UP ZONE. Terry, Elizabeth G. // Turtle;Jul/Aug2012, Vol. 34 Issue 4, p32 

    The article offers information and tips for parents and teachers including protecting preschoolers from the sun's ultraviolet rays and making kindergarten exciting for a child.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics