TITLE

Torturing a blood vessel

AUTHOR(S)
Patterson, Cam
PUB. DATE
February 2009
SOURCE
Nature Medicine;Feb2009, Vol. 15 Issue 2, p137
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on research into cerebral cavernous malformations (CCM) and efforts to develop animal models to study the condition. It states that three mutated genes have been identified in CCMs. It mentions that the proteins that these genes are responsible to mediate cellular responses to stress that requires Rho-family GTPase activation and mitogen-activated protein kinase signaling. It comments on the difficulty in developing animal models that mimic the lesions found in CCM patients.
ACCESSION #
36386741

 

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