Pathogenesis of Staphylococcal Infection: A Manner of Expression

Chambers, Henry F.
February 2009
Journal of Infectious Diseases;2/1/2009, Vol. 198 Issue 3, p291
Academic Journal
The article discusses the pathogenesis of Staphylococcal infection in a manner of expression. It states that Staphylococcus aureus owes its success as a pathogen in humans to about 100 specific factors that allow it to evade host defenses. It notes that the genes encoding virulence factors are frequently located on mobile genetic elements such as a prophage, pathogenecity island or plasmid. It adds that some factors can be found in all strains but the presence of others varies from strain to strain. It stresses that genes are regulated and integrated into the overall cellular program.


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