TITLE

Pathogenesis of Staphylococcal Infection: A Manner of Expression

AUTHOR(S)
Chambers, Henry F.
PUB. DATE
February 2009
SOURCE
Journal of Infectious Diseases;2/1/2009, Vol. 198 Issue 3, p291
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the pathogenesis of Staphylococcal infection in a manner of expression. It states that Staphylococcus aureus owes its success as a pathogen in humans to about 100 specific factors that allow it to evade host defenses. It notes that the genes encoding virulence factors are frequently located on mobile genetic elements such as a prophage, pathogenecity island or plasmid. It adds that some factors can be found in all strains but the presence of others varies from strain to strain. It stresses that genes are regulated and integrated into the overall cellular program.
ACCESSION #
36327980

 

Related Articles

  • Messenger RNA Turnover Processes in Escherichia coli, Bacillus subtilis, and Emerging Studies in Staphylococcus aureus. Anderson, Kelsi L.; Dunman, Paul M. // International Journal of Microbiology;2009, p1 

    The regulation of mRNA turnover is a recently appreciated phenomenon by which bacteria modulate gene expression. This review outlines the mechanisms by which three major classes of bacterial trans-acting factors, ribonucleases (RNases), RNA binding proteins, and small noncoding RNAs (sRNA),...

  • Extensive Adaptive Changes Occur in the Transcriptome of Streptococcus agalactiae (Group B Streptococcus) in Response to Incubation with Human Blood. Mereghetti, Laurent; Sitkiewicz, Izabela; Green, Nicole M.; Musser, James M. // PLoS ONE;2008, Vol. 3 Issue 9, p1 

    To enhance understanding of how Streptococcus agalactiae (group B streptococcus, GBS) adapts during invasive infection, we performed a whole-genome transcriptome analysis after incubation with whole human blood. Global changes occurred in the GBS transcriptome rapidly in response to blood...

  • Insights into the Staphylococcus aureus-Host Interface: Global Changes in Host and Pathogen Gene Expression in a Rabbit Skin Infection Model. Malachowa, Natalia; Kobayashi, Scott D.; Sturdevant, Daniel E.; Scott, Dana P.; DeLeo, Frank R. // PLoS ONE;Feb2015, Vol. 10 Issue 2, p1 

    Staphylococcus aureus is an important cause of human skin and soft tissue infections (SSTIs) globally. Notably, 80% of all SSTIs are caused by S. aureus, of which ∼63% are abscesses and/or cellulitis. Although progress has been made, our knowledge of the host and pathogen factors that...

  • Enhanced Monocyte Response and Decreased Central Memory T Cells in Children with Invasive Staphylococcus aureus Infections. Ardura, Monica I.; Banchereau, Romain; Mejias, Asuncion; Di Pucchio, Tiziana; Glaser, Casey; Allantaz, Florence; Pascual, Virginia; Banchereau, Jacques; Chaussabel, Damien; Ramilo, Octavio // PLoS ONE;2009, Vol. 4 Issue 5, p1 

    Staphylococcus aureus has emerged as a significant pathogen causing severe invasive disease in otherwise healthy people. Despite considerable advances in understanding the epidemiology, resistance mechanisms, and virulence factors produced by the bacteria, there is limited knowledge of the in...

  • How Pathogens Hijack Host Plants.  // Asian Journal of Plant Sciences;2011, Vol. 10 Issue 2, p166 

    No abstract available.

  • Role and regulation of heme iron acquisition in gram-negative pathogens. Runyen-Janecky, Laura J. // Frontiers in Cellular & Infection Microbiology;Oct2013, Vol. 3, p1 

    Bacteria that reside in animal tissues and/or cells must acquire iron from their host. However, almost all of the host iron is sequestered in iron-containing compounds and proteins, the majority of which is found within heme molecules. Thus, likely iron sources for bacterial pathogens (and...

  • Microarray Analysis of the Intestinal Host Response in Giardia duodenalis Assemblage E Infected Calves. Dreesen, Leentje; Rinaldi, Manuela; Chiers, Koen; Li, Robert; Geurden, Thomas; Broeck, Wim Van den; Goddeeris, Bruno; Vercruysse, Jozef; Claerebout, Edwin; Geldhof, Peter // PLoS ONE;Jul2012, Vol. 7 Issue 7, p1 

    Despite Giardia duodenalis being one of the most commonly found intestinal pathogens in humans and animals, little is known about the host-parasite interactions in its natural hosts. Therefore, the objective of this study was to investigate the intestinal response in calves following a G....

  • Staphylococcus aureus mobile genetic elements. Alibayov, Babek; Baba-Moussa, Lamine; Sina, Haziz; Zdeňková, Kamila; Demnerová, Kateřina // Molecular Biology Reports;Aug2014, Vol. 41 Issue 8, p5005 

    Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition,...

  • The Staphylococcus aureus Response to Unsaturated Long Chain Free Fatty Acids: Survival Mechanisms and Virulence Implications. Kenny, John G.; Ward, Deborah; Josefsson, Elisabet; Jonsson, Ing-Marie; Hinds, Jason; Rees, Huw H.; Lindsay, Jodi A.; Tarkowski, Andrej; Horsburgh, Malcolm J. // PLoS ONE;2009, Vol. 4 Issue 2, p1 

    Staphylococcus aureus is an important human commensal and opportunistic pathogen responsible for a wide range of infections. Long chain unsaturated free fatty acids represent a barrier to colonisation and infection by S. aureus and act as an antimicrobial component of the innate immune system...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics