TITLE

NEW FACETS OF THE RENIN-ANGIOTENSIN SYSTEM

AUTHOR(S)
Haulica, I.; Bild, W.; Popescu, R.
PUB. DATE
April 2007
SOURCE
Acta Endocrinologica (1841-0987);Apr-Jun2007, Vol. 3 Issue 2, p225
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article offers information on the enzymatic cascade for the circulating and local biosynthesis of angiotensin peptides. There are two categories of tissue renin-like enzymes, the tissue cathepsins G, E and D and the tissue renin-like enzymes represented by tonin. Aside from carboxypeptidases, neural endopeptidase, and prolyl endopeptidase, the aminopeptidases participate as angiotensinases in the biochemical pathway of angiotensin peptide inactivation. It was found that many tissues and organs of an intrinsic angiotensin-generating system is responsive for the locally-formed bioactive angiotensins.
ACCESSION #
36320638

 

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