TITLE

Two Cases of Tuberculosis Complicating Treatment With Tumor Necrosis Factor-α Inhibitors

AUTHOR(S)
Çalıkoğlu, Mukadder; Şahin, Günsah; Aslan, Gönül
PUB. DATE
September 2008
SOURCE
Turk Toraks Dergisi / Turkish Thoracic Journal;Sep2008, Vol. 9 Issue 3, p133
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
TNF-α blocking agents have been increasingly used in the treatment of systemic inflammatory diseases. The main adverse effect of these drugs is susceptibility to infections, mainly reactivation of latent tuberculous infection (LTBI). In this paper we described two cases of TNF-α inhibitor-associated TB. Because LTBI and BCG vaccination are widespread in the Turkish population, a stringent pre-treatment screening protocol for LTBI should be used. In such patients, TB frequently presents as an extrapulmonary or disseminated and life-threatening disease. Physicians should be aware of the risk of the reactivation of TB, despite isoniazid chemoprophylaxis, with unusual clinical manifestations and a paradoxical response.
ACCESSION #
36314583

 

Related Articles

  • Development of bilateral chylothorax in a younger female secondary to tuberculosis. Kant, Surya; Verma, Sanjay Kumar; Anand, Sunish C.; Prasad, Rajendra; Verma, Rajendra Kumar // Lung India;Jan-Mar2011, Vol. 28 Issue 1, p56 

    Chylothorax is a rare clinical entity characterized by a milky white aspirate with increased triglyceride levels. The commonest etiology is malignancy and trauma, and bilateral chylothorax, secondary to tuberculosis, is an extremely rare cause, as observed in the present case.

  • Investigation of Environmental and Host-related Risk Factors for Tuberculosis in Africa. I. Methodological Aspects of a Combined Design. Lienhardt, C.; Bennett, S.; Del Prete, G.; Bah-Sow, O.; Newport, M.; Gustafson, P.; Manneh, K.; Gomes, V.; Hill, A.; McAdam, K. // American Journal of Epidemiology;Jun2002, Vol. 155 Issue 11, p1066 

    Host-related and environmental factors for tuberculosis have usually been investigated separately using different study designs. Joint investigation of the genetic, immunologic, and environmental factors at play in susceptibility to tuberculosis represents an innovative goal for obtaining a...

  • Recurrent aphthous stomatitis: genetic aspects of etiology. Ślebioda, Zuzanna; Szponar, Elżbieta; Kowalska, Anna // Advances in Dermatology & Allergology / Postepy Dermatologii i A;2013, Vol. 30 Issue 2, p96 

    Recurrent aphthous stomatitis (RAS; recurrent aphthous ulcers -- RAU; canker sores) is a chronic inflammatory, ulcerative condition of the oral mucosa. Its prevalence in the general population ranges between 5% and 20%, depending on the method and group studied. The etiopathogenesis of the...

  • Uremic stomatitis. Sudarshan, Ramachandran; Annigeri, Rajeshwari G.; Mamatha, G. P.; Sree Vijayabala, G. // Contemporary Clinical Dentistry;Jan-Mar2012, Vol. 3 Issue 1, p113 

    Uremic stomatitis is a rare mucosal disorder associated with renal disorders. Here, we report a case of a 42-year-old male patient suffering from diabetes, angina pectoris, with white curdly pseudomembrane over the dorsal surface of the tongue, which was diffuse. The etiology, clinical features,...

  • gastroenteritis. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p332 

    An encyclopedia entry for "gastroenteritis" is presented. It refers to the inflammation of the stomach and intestines, usually causing sudden upsets that lasts for two or three days. Forms of gastroenteritis include dysentery, typhoid fever, cholera, food poisoning and travellers' diarrhoea. The...

  • Mendelian Susceptibility to Mycobacterial Disease in Egyptian Children. Galal, Nermeen; Boutros, Jeannette; Marsafy, Aisha; Xiao-Fei Kong; Feinberg, Jacqueline; Casanova, Jean-Laurent; Boisson-Dupuis, Stéphanie; Bustamante, Jacinta // Mediterranean Journal of Hematology & Infectious Diseases;2012, Vol. 4 Issue 1, p1 

    Background: Tuberculosis remains a major health problem in developing countries especially with the emergence of multidrug resistant strains. Mendelian Susceptibility to Mycobacterial Disease (MSMD) is a rare disorder with impaired immunity against mycobacterial pathogens. Reported MSMD...

  • There's a change in the epidemiology of TB in the United States.  // Contemporary Pediatrics;Nov2005, Vol. 22 Issue 11, p86 

    This article reports on the change in the epidemiology of tuberculosis (TB) in the U.S. as of November 2005. Since 1992, the case rate of TB has declined overall. In 1993, the case rate for children from birth to 4 years of age was 5.5 per 100,000 and, for children 5 to 14 years old, 1.7 per...

  • Is micropapular sarcoidosis tuberculosis? Ridgway, Hilary A.; Ryan, Terence J. // Journal of the Royal Society of Medicine;Feb1981, Vol. 74 Issue 2, p140 

    Three cases of micropapular sarcoidosis are reported. Two of the cases have a history of tuberculosis and all three cases have atypical patterns of Kveim and Mantoux reactivity. The similarities between this form of sarcoidosis and lichen scrofulosorum or lichenoid tuberculid are observed and...

  • Association between recurrent aphthous stomatitis and Helicobacter pylori infection: a meta-analysis. Li, Lin; Gu, Huiyuan; Zhang, Guoxin // Clinical Oral Investigations;Jul2014, Vol. 18 Issue 6, p1553 

    Objectives: Several studies have shown the possible involvement of Helicobacter pylori infection in individuals with recurrent aphthous stomatitis (RAS), but the relationship remains controversial. This meta-analysis was performed to validate the association between RAS and H. pylori infection....

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics