TITLE

HLA — oriented therapy for gastric cancer A novel approach therapy

AUTHOR(S)
SISU, Roxana
PUB. DATE
December 2008
SOURCE
Maedica - a Journal of Clinical Medicine;2008, Vol. 3 Issue 4, p301
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on the use of human leukocyte antigens (HLA) for the treatment of gastric cancer. HLA are glycoproteins found on the surface membrane of cell in the body. They help the immune system defend against cancers, viruses, bacteria, and parasites. In a study, HLA antigens were examined in gastric cancer patients before surgery, and the surgical outcomes were evaluated. The therapies consisted of gastrectomy, a chemotherapy group and an immunotherapy group. The study showed that there was an important clinical impact of determining HLA antigens before surgery.
ACCESSION #
36124669

 

Related Articles

  • Aspirin's benefits linked to HLA class I expression in colorectal cancer.  // Hem/Onc Today;11/10/2013, Vol. 14 Issue 21, p14 

    The article focuses on a study on gastrointestinal cancer and the link between the benefits of aspirin and human leukocyte antigen class I expression in colorectal cancer discussed during the European Cancer Congress held in Amsterdam, Netherlands from September 27 to October 1, 2013,

  • Sensitization of tumour cells to lysis by virus-specific CTL using antibody-targeted MHC class I/peptide complexes. Ogg, G S; Dunbar, P R; Cerundolo, V; McMichael, A J; Lemoine, N R; Savage, P // British Journal of Cancer;3/1/2000, Vol. 82 Issue 5, p1058 

    A number of cell surface molecules with specificity to tumour cells have been identified and monoclonal antibodies (mAb) to some of these antigens have been used for targeting tumour cells in vivo. We have sought to link the powerful effector mechanisms of cytotoxic T-cells with the specificity...

  • Haematopoietic cell transplantation as immunotherapy. Appelbaum, Frederick R. // Nature;5/17/2001, Vol. 411 Issue 6835, p385 

    Presents a study which focused on cancer immunotherapy using allogeneic haematopoietic cell transplantation. Role of the major histocompatibility complex in the immunological reactions during transplantation of allogeneic haematopoietic; Importance of the human leukocyte antigen compatibility...

  • A modular concept of HLA for comprehensive peptide binding prediction. DeLuca, David S.; Khattab, Barbara; Blasczyk, Rainer // Immunogenetics;Jan2007, Vol. 59 Issue 1, p25 

    A variety of algorithms have been successful in predicting human leukocyte antigen (HLA)-peptide binding for HLA variants for which plentiful experimental binding data exist. Although predicting binding for only the most common HLA variants may provide sufficient population coverage for vaccine...

  • HLA class I alleles in HTLV-1-associated myelopathy and asymptomatic carriers from the Brazilian cohort GIPH. Catalan-Soares, B. C,; Carneiro-Proietti, Anna Bárbara F.; Da Fonseca, F.G.; Correa-Oliveira, R.; Peralva-Lima, D.; Portela, R.; Ribas, J. G.; Gonçalves, D. U.; Proietti, F. // Medical Microbiology & Immunology;Feb2009, Vol. 198 Issue 1, p1 

    The development of HTLV-1-associated myelopathy (HAM/TSP) in HTLV-1-infected individuals is probably a multi-factor event, in which the immune system plays a crucial role. The efficiency of the host immunity seems to be one of the in vivo determining factors of the proviral load levels and is...

  • human leukocyte antigen (HLA). Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p389 

    A definition of the term "human leukocyte antigen (HLA)," which refers to a protein that belongs to the group of proteins called histocompatibility antigens which play a role in the immune system, is presented.

  • histocompatibility antigens. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p383 

    An encyclopedia entry for "histocompatibility antigens" is presented. It refers to a group of proteins that have role in the immune system. There are certain types of histocompatibility antigen present in the cells of the body and they are vital for the immunological function of killer T cells a...

  • Analysis of HLA class Ia transcripts in human leukaemias. Majumder, Durjoy; Bandyopadhyay, Debasis; Chandra, Sarmila; Mukhopadhayay, Ashis; Mukherjee, Nandini; Bandyopadhyay, Subir; Banerjee, Subrata // Immunogenetics;Sep2005, Vol. 57 Issue 8, p579 

    Several leukaemia-specific antigens have been discovered in the recent past, which raised the possibility for T-cell-based immunotherapy for leukaemia. However, failure of such approaches involving interleukin-2 and/or T-cell-based immunotherapy indicated the importance of investigation of the...

  • Influence of Host Genetics on the Severity of Coccidioidomycosis. Louie, Leslie; Ng, Susanna // Emerging Infectious Diseases;Sep/Oct99, Vol. 5 Issue 5, p672 

    Coccidioidomycosis, a mild flulike illness in approximately 40% of infected persons, progresses to severe pulmonary or disseminated disease in 1% to 10% of symptomatic cases. We examined host genetic influences on disease severity among class II HLA loci and the ABO blood group. Participants...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics