TITLE

Chemical synthesis: Take that, flu

PUB. DATE
January 2009
SOURCE
Nature;1/15/2009, Vol. 457 Issue 7227, p239
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses research conducted by Yujiro Hayashi and his team at the Tokyo University of Science on the cheapest, most efficient route by which to make the influenza drug Tamiflu. Hayashi's methodology utilizes inexpensive reagents and only nine reactions. This process uses diphenylprolinol silyl ether, an organocatalyst that doesn't involve toxic metals.
ACCESSION #
36113317

 

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