Metastatic Renal Cell Carcinoma to the Head and Neck: Summary of 21 Cases

Langille, Gavin; Taylor, S. Mark; Bullock, Martin J.
August 2008
Journal of Otolaryngology -- Head & Neck Surgery;Aug2008, Vol. 37 Issue 4, p515
Academic Journal
Objective: Metastasis of renal cell carcinoma (RCC) to the head and neck is a relatively uncommon phenomenon, but such lesions can be the initial presentation of disease. RCC should be considered a source for lesions in this region, especially in patients who have received a previous diagnosis of RCC. Methods: In this study, we review the presentation, management, and outcomes for 21 patients with documented metastasis of RCC to the head and neck outside the central nervous system. This study is a retrospective review of cases ascertained during a 17-year period from a large teaching hospital. Results: Of the 21 patients observed, 10 were found to have metastatic disease at the time of RCC diagnosis, involving the head and neck in 5 cases. The most common sites of head and neck metastasis were to bone (n = 6), skin and subcutaneous tissue (n = 6), and lymph nodes (n = 5). Conclusions: This study is a reminder to consider a renal primary tumour for metastatic disease identified in the head and neck, particularly metastases with a "clear cell" histologic pattern. A head and neck metastasis may occasionally be the presenting sign in a patient with RCC, or it may follow the primary diagnosis by many years.


Related Articles

  • Bbrek hcreli kanserde "omental cake" oluÅŸumu: Olgu sunumu ve literatrn gzden geirilmesi. Kuzgunbay, Barış; Gören, Mehmet Reşit; Güvel, Sezgin // Turkish Journal of Urology;Jun2011, Vol. 37 Issue 2, p180 

    Peritoneal and omental metastasis are rare types of metastasis for renal cell carcinoma (RCC). In this report, we present a 72-year old women with omental cake formation due to omentum metastasis of RCC and review the literature.

  • Bases moleculares de la enfermedad de von Hippel-Lindau. SÁENZ, MARÍA PAULA // Universitas Médica;jul-sep2008, Vol. 49 Issue 3, p408 

    Von Hippel-Lindau disease is an autosomal dominant disorder that is characterized by the development of various benign and malignant tumors and cysts, in the central nervous system, retinal hemangioblastoma, pheocromocytoma and renal cell carcinoma. The VHL tumor suppressor gene, which is...

  • Somatic gain-of-function HIF2A mutations in sporadic central nervous system hemangioblastomas. Taïeb, David; Barlier, Anne; Yang, Chunzhang; Pertuit, Morgane; Tchoghandjian, Aurélie; Rochette, Claire; Zattara-Canoni, Hélène; Figarella-Branger, Dominique; Zhuang, Zhengping; Pacak, Karel; Metellus, Philippe // Journal of Neuro-Oncology;Feb2016, Vol. 126 Issue 3, p473 

    Central nervous system hemangioblastomas (CNS-HBs) occur sporadically or as a component of von Hippel-Lindau-VHL syndrome. CNS-HBs share some molecular similarities with pheochromocytomas/paragangliomas (PPGLs) and renal cell carcinomas (RCCs). Recently, hypoxia-inducible factors, particularly...

  • Diagnosis of Metastatic Renal Cell Carcinoma on Fine-Needle Aspiration Cytology. Lew, Madelyn; Wen-Chi Foo; Roh, Michael H. // Archives of Pathology & Laboratory Medicine;Oct2014, Vol. 138 Issue 10, p1278 

    Fine-needle aspiration has assumed an increasingly important role in the diagnosis and management of patients with advanced stage cancer. Given its predilection for metastases to distant sites and organs at the time of presentation, metastatic renal cell carcinoma (RCC) is not infrequently...

  • Renal cell cancer: nurses' role in prevention and management. Noble, Helen; Page, Karen // British Journal of Nursing;9/27/2012 Supplement, pS18 

    In both the UK and throughout Europe, more patients are presenting with renal cell cancer (RCC), also known as renal cell carcinoma or kidney cancer. The overall survival rate varies depending on tumour grade, nodal involvement and metastasis. For those with metastasis survival drops to 10%....

  • Von Hippel-Lindau Hastalığının Sıradışı Oküler Prezantasyonu.  // Retina-Vitreus/Journal of Retina-Vitreous;Dec2010, Vol. 18 Issue 4, p314 

    No abstract available.

  • The Value of a Routine Bone Scan in a Metastatic Survey. Brown, Dale H.; Leakos, Mark // Journal of Otolaryngology;Jul/Aug1998, Vol. 27 Issue 4, p187 

    Evaluates the benefits of routine bone scanning preoperatively in patients with squamous cell carcinoma of the head and neck. Retrospective analysis of a number of patients undergoing a bone scan with respect to indication, diagnosis, scan result and tumor stage; Implication of the incidence of...

  • Metastatic renal cell carcinoma to the third ventricle resembling a colloid cyst. Wagner, Kate; Thompson, Eric; Ragel, Brian // Acta Neurochirurgica;Apr2013, Vol. 155 Issue 4, p737 

    A letter to the editor about a case report of a 64-year-old male patient with metastatic renal cell carcinoma (RCC) is presented.

  • Radiation oncology.  // Clinical & Investigative Medicine;Aug97 Supplement, Vol. 20, pS92 

    Presents an abstract of the research manuscript `Pretreatment study of oxygen tension in nodal metastases in patients with head and neck cancer--preliminary results,' by F.G. Sheehan et al.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics