Saba, Laura; Hoffman, Paula L.; Hornbaker, Cheryl; Bhave, Sanjiv V.; Tabakoff, Boris
September 2008
Alcohol Research & Health;2008, Vol. 31 Issue 3, p272
Academic Journal
Researchers from a wide variety with a broad range of goals hthroughput screening technotechnologies) to identify candidate gated with an observable characteristinotype) of interest. However, the ini y of backgrounds and ave utilized high-logies (i.e., microarray enes that may be associc or behavior (i.e., phetial microarray analyses typically also yield many genes that are not related to the phenotype of interest. Therefore, additional analyses are necessary to select the most likely candidates and eventually identify one or more genes that actually underlie that phenotype. After briefly explaining how microarray data are generated, this article describes one approach to narrowing down the resulting candidate genes and a database that can help in this analysis.


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