Sanković-Babić, Snežana; Atanasković-Marković, Marina; Kosanović, Rade
December 2008
Acta Medica Saliniana;2008, Vol. 37 Issue 2, p166
Academic Journal
Introduction: According to recent studies the role of allergy in ethipathogenesis of secretory otitis media is the leading one. The incidence of allergy in secretory otitis media varies from 57% to 100% according to recent studies. The allergic inflammation of the middle aer mucosa is of Th 2 type inflammation of respiratory mucosa. Increased number of activated mast cells, mastocyte tryptase, eosinophyllic cationic protein and mRNA for IL 5 were found in mucosa and effusion in SOM. The aim of this sudy was to investigate the presence of allergies in children with secertory otitis media and to follow up the outcome after antoallergic therapy. Patients and Methods: In this study 71 children with SOM entered the diagnostic procedure for allergy tests. Clinical examination by alergologist, skin prick test, sIgE, eosinophils in nasal lavage were performed. Allergy management was introduced in group of 38 (54%) children with diagnosis of allergy and secretory otitis media. Antihistamines, intranasal cortocosteroids, and elimination of identified antigen were the first line therapy . Results: After follow up period of three months in 21(47%) children out of 38 with allergy an secretory otitis the complete recovery of middle ear function was seen. After follow up period of 6 months in 27 (61%) children was noticed complete recovery and the rest of 17 children underwent surgical therapy. Discussion and Conclusion: Allergy screening is not conventional tool in diagnosis of secretorz otiti media. The results of this study as well as results of other clinicall studies implies to introduction allergzy tests in clonicall diagnostic procedure Antiallergic therapy can contribute to conservative management of disease and decrease the number of patient for surgical therapy.


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