2008 - Tibolone reduced risk for fractures and breast cancer but increased risk for stroke in older women with osteoporosis

Kauffman, Robert P.
November 2008
ACP Journal Club;11/18/2008, Vol. 149 Issue 5, p6
Academic Journal
The article presents information on a study conducted to find out if tibolone reduces risk for vertebral fractures in older women with osteoporosis. Tibolone is a unique selective estrogen, progesterone and androgen-receptor modulator that is widely marketed worldwide. Patients included 4538 women belonging to 60 to 85 years of age who had a bone mineral density T score of -2.5 at the hip or spine, or T score of -2.0 and radiologic evidence of a vertebral fracture.


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