2008 - Review: Anticoagulation with INRs less than 2 or between 3 and 5 increases risk for thromboembolic or hemorrhagic events

Holbrook, Anne
November 2008
ACP Journal Club;11/18/2008, Vol. 149 Issue 5, p3
Academic Journal
The article presents information on a study conducted to find out the effect of anticoagulation intensity on risk for thromboembolism or hemorrhage in patients taking oral anticoagulants. The journal reviewed included MEDLINE, EMBASE/Excerpta Medica, CINAHL, and Cochrane Central Register of Controlled Trials. Studies selected evaluated OA therapy for various indications and reported the number of outcome events. The main conclusion of the meta-analysis revealed that it is not controversial.


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