TITLE

Chiral ligand-exchange chromatography of amino acids using porous graphitic carbon coated with a dinaphthyl derivative of neamine

AUTHOR(S)
Zaher, Mustapha; Ravelet, Corinne; Baussanne, Isabelle; Ravel, Anne; Grosset, Catherine; Décout, Jean-Luc; Peyrin, Eric
PUB. DATE
January 2009
SOURCE
Analytical & Bioanalytical Chemistry;Jan2009, Vol. 393 Issue 2, p655
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In this paper, we describe the preparation and the evaluation of a porous graphitic carbon (PGC) column coated with a new dinaphthyl derivative of neamine for chiral ligand-exchange (LE) chromatography. It was shown that the graphitic surface/dinaphthyl anchor system efficiently (1.15 μmol/m2) and stably (three months of intensive use) adsorbs the neamine template onto the chromatographic support. The resulting coated PGC stationary phase showed appreciable LE-based enantioselective properties towards several native amino acids. [Figure not available: see fulltext.]
ACCESSION #
35774229

 

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