Lateral-driven continuous magnetophoretic separation of blood cells

Jinhee Jung; Ki-Ho Han
December 2008
Applied Physics Letters;12/1/2008, Vol. 93 Issue 22, p223902
Academic Journal
We present a method for the lateral-driven continuous magnetophoretic separation of red and white blood cells from peripheral whole blood, based on their native magnetic properties. The separation is achieved using a high-gradient magnetic field, caused by a ferromagnetic wire array inlaid on glass substrate. The wire array creates an even lateral magnetophoretic force on the whole area of the microchannel, improving the separation efficiency and throughput. When the flow rate and external magnetic flux were 20 μl/h and 0.3 T, respectively, the microseparator continuously separated out 93.9% of red blood cells and 89.2% of white blood cells from the whole blood.


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