Early evaluation of patient risk for substantial weight gain during olanzapine treatment for schizophrenia, schizophreniform, or schizoaffective disorder
- Metformin for Prevention of Weight Gain and Insulin Resistance With Olanzapine: A Double-Blind Placebo-Controlled Trial. Baptista, Trino; Martínez, Jessan; Lacruz, Anny; Rangel, Nairy; Beaulie, Serge; Serrano, Ana; Arapé, Yinet; Martinez, Maritza; de Mendoza, Soaira; Teneud, Luis; Hernández, Luis // Canadian Journal of Psychiatry;Mar2006, Vol. 51 Issue 3, p192
Objective: To assess whether metformin prevents body weight gain (BWG) and metabolic dysfunction in patients with schizophrenia who are treated with olanzapine. Method: Forty patients taking olanzapine (10 mg daily) were randomly allocated to a metformin (n = 20; 850 to 1700 mg daily) or placebo...
- Impact of race on efficacy and safety during treatment with olanzapine in schizophrenia, schizophreniform or schizoaffective disorder. Stauffer, Virginia L.; Sniadecki, Jennifer L.; Piezer, Kevin W.; Gatz, Jennifer; Kollack-Walker, Sara; Hoffmann, Vicki Poole; Conley, Robert; Durell, Todd // BMC Psychiatry;2010, Vol. 10, p89
Background: To examine potential differences in efficacy and safety of treatment with olanzapine in patients with schizophrenia of white and black descent. Methods: A post-hoc, pooled analysis of 6 randomized, double-blind trials in the treatment of schizophrenia, schizophreniform disorder, or...
- BDNF Levels and Genotype are Associated with Antipsychotic-Induced Weight Gain in Patients with Chronic Schizophrenia. Xiang Yang Zhang; Dong Feng Zhou; Gui Ying Wu; Lian Yuan Cao; Yun Long Tan; Haile, Colin N.; Li, Jun; Lin Lu; Kosten, Therese A.; Kosten, Thomas R. // Neuropsychopharmacology;Sep2008, Vol. 33 Issue 10, p2200
Recent evidence suggests that centrally released brain-derived neurotrophic factor (BDNF) modulates eating behavior and metabolism that is responsible for body weight fluctuation. BDNF also may play an important role in the therapeutic action of antipsychotic medications. We investigated whether...
- Individual dietary education reduces olanzapine associated weight gain. Evans, S.; Newton, R.; Higgins, S. // Evidence Based Mental Health;Feb2006, Vol. 9 Issue 1, p11
The article reports on a study showing that individual dietary education delivered by a dietitian reduces weight gain in people beginning olanzapine treatment. The results of the follow up of the study after three months were not reported due to high loss to follow up. Individual dietary...
- Factors associated with early response to olanzapine and clinical and functional outcomes of early responders treated for schizophrenia in the People's Republic of China. Wenyu Ye; Montgomery, William; Kadziola, Zbigniew; Li Liu; Haibo Xue; Stensland, Michael D.; Treuer, Tamas // Neuropsychiatric Disease & Treatment;2014, Vol. 10, p869
Background: The aims of this analysis were to identify factors associated with early response (at 4 weeks) to olanzapine treatment and to assess whether early response is associated with better longer-term outcomes for patients with schizophrenia in the People's Republic of China. Methods: A...
- Gaining weight for three. FAULKNER, JEANNE // Fit Pregnancy;Aug/Sep2011, Vol. 18 Issue 3, p124
The article reports on updated weight-gain guidelines from the U.S. Institute of Medicine for women pregnant with twins, which are based on the prepregnancy Body Mass Index (BMI) of the pregnant woman.
- Do You Need To Lose Weight? // Healthy Hearts, Healthy Homes - Do You Need to Lose Weight?;2008, preceding p1
This publication discusses the health benefits of weight loss. It discusses the reasons of weight gain and offers step-by-step instructions on how to identify if one needs to lose weight. A diagram showing the Body Mass Index (BMI) is shown. It also offers tips on how to lose unwanted weight. It...
- AVOID POST-BABY WEIGHT GAIN. S. R. // Fit Pregnancy;Oct/Nov2011, Vol. 18 Issue 4, p32
The article offers information on the study conducted, which revealed the role played by body mass index (BMI) in reducing the post-pregnancy weight gain.
- Weight Gain Among Men and Women College Students. // Women in Academia Report;10/16/2012, p8
The article presents a study on the association between weight gain and body mass index of college students by the Auburn University.