Application of microarray outlier detection methodology to psychiatric research
- Microarrays in Brain Research: Data Quality and Limitations. Mirnics, K�roly // Current Genomics;Feb2002, Vol. 3 Issue 1, p13
In the post-genomic era, microarray technology will have a major impact on our understanding of complex gene expression patterns and circuit function in the brain. Due to the phenotypic and transcript complexity of the brain, transcriptome profiling data is multifaceted, and is best interpreted...
- Expressing what's on your mind: DNA arrays and the brain. Lockhart, David J.; Barlow, Carrolee // Nature Reviews Genetics;Mar2004 Microarrays, Vol. 5, p41
Discusses the genomic approaches in the study of brain function and disease and the use of DNA arrays. Primary goal of neurogenetics; Two dominant types of DNA arrays; Information on the complementary approach to find genes that are expressed in the brain; Considerations when doing parallel...
- Inference of combinatorial Boolean rules of synergistic gene sets from cancer microarray datasets. Park, Inho; Lee, Kwang H.; Lee, Doheon // Bioinformatics;Jun2010, Vol. 26 Issue 12, p1506
Motivation: Gene set analysis has become an important tool for the functional interpretation of high-throughput gene expression datasets. Moreover, pattern analyses based on inferred gene set activities of individual samples have shown the ability to identify more robust disease signatures than...
- Thunder Bay expanding knowledge. // Northern Ontario Business;Nov2005, Vol. 26 Issue 1, p10
Reports that a new microarray laboratory has been unveiled in the lower tower of the Northwestern Ontario Technology Center in Thunder Bay, Ontario, in 2005.
- Microarrays and macroconsequences. Collins, Francis S // Nature Genetics;Jan99 Supplement, Vol. 21, p2
Discusses the articles published in the January 1999 supplement issue of the journal 'Nature Genetics.' Advances in technology for the production of nucleic acid microarrays in various formats; Impact of microarrays on the understanding of biology.
- Microarray databases: standards and ontologies. Stoeckert, Christian J.; Causton, Helen C.; Ball, Catherine A. // Nature Genetics;Dec2002 Supplement 2, Vol. 32, p469
A single microarray can provide information on the expression of tens of thousands of genes. The amount of information generated by a microarray-based experiment is sufficiently large that no single study can be expected to mine each nugget of scientific information. As a consequence, the scale...
- Community watch. // Nature Genetics;May2001, Vol. 28 Issue 1, p1
Describes the methods used to analyze DNA microarray data. Development of the PubGene program; Use of gene symbols representing human and mouse genes; Establishment of a standard set of words that describe information relevant to gene function.
- Jets: a modification to speed flexible oligonucleotide array construction. Yoder, B.; Sell, S.M. // Pharmacogenomics Journal;2001, Vol. 1 Issue 3, p163
Discusses research led by T.R. Hughes on the use of in situ ink-jet oligonucleotide synthesis for array construction. Application of the microarray technology; Limitation of the oligonucleotide set design method described by Hughes; Flexibility of the system described by Hughes.
- Complaints raised over restricted microarray access. Fox, Jeffrey L. // Nature Biotechnology;Apr99, Vol. 17 Issue 4, p325
Reports that some research biologists are complaining among themselves and to federal officials that access to microarray analysis is being unfairly restricted as of April 1999. Impact of these restrictions on their ability to learn more about the working of genes and chromosomes; Researchers'...