SADHART-CHF: no difference in HF events with sertraline

November 2008
Cardiology Today;Nov2008, Vol. 11 Issue 11, p18
The article reports on the Safety and Efficacy of Sertraline for Depression in Patients with Congestive Heart Failure (SADHART-CHF) study which revealed that patients with depression and CHF did not have additional benefit with sertraline. In the trial, Dr. Christopher O'Connor states that sertraline plus nurse-facilitated supportive intervention was equal to nurse-facilitated supportive intervention alone, and that no benefit or harm was seen for nonfatal cardiovascular (CV) events.


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