TITLE

Splenectomy for Splenic Metatases: A Changing Clinical Spectrum

AUTHOR(S)
Lee, Steven S.; Morgenstern, Leon; Phillips, Edward H.; Hiatt, Jonathan R.; Margulies, Daniel R.
PUB. DATE
September 2000
SOURCE
American Surgeon;Sep2000, Vol. 66 Issue 9, p837
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Splenic metastases from solid tumors are unusual with only scattered case reports of patients treated with splenectomy before 1987. We conducted a retrospective chart review at our large tertiary-care private teaching hospital between January 1990 and September 1999 and found splenic metastases in 31 patients. In eight patients (26%), the spleen was the only site of metastatic disease. Of the 31 splenectomies for metastases, 23 were performed for ovarian neoplasms, five during primary operative procedures, and 18 during secondary cytoreductive procedures or explorations for late recurrences at an average of 3.9 years after the original operation. Nearly half of the metastases (15 of 31) appeared entirely within the splenic parenchyma, representing probable hematogenous spread, whereas seven involved both the splenic parenchyma and capsule and nine involved the capsule only. Between 1990 and 1999 we identified a statistically significant increase in use of splenectomy for treatment of metastatic tumor with a Spearman rank correlation value of 0.86 (P < 0.05). Most of this increase was attributable to ovarian cancer cases and may be due to expansion of treatment options or improved imaging methods. We report the largest series of splenectomy for splenic metastases and the ninth case report in the world literature of splenectomy for isolated splenic metastasis due to colorectal cancer.
ACCESSION #
3554419

 

Related Articles

  • Wandering Spleen with Huge Splenomegaly: a Diagnostic Challenge. Shahi, K. S.; Geeta, Bhandari; Rajput, P. // Internet Journal of Surgery;2009, Vol. 19 Issue 2, p30 

    Wandering spleen is a rare clinical entity characterized by mal-development of suspensory ligaments and elongation of the splenic pedicle which result in a mobile spleen. It is seen in women of child-bearing age and in children below 10 years of age. We report a case of a 30-year-old female with...

  • Non-interventional management of splenic abscess. Kumar, Saket; Gupta, Vishal; Medappil, Noushif; Chandra, Abhijit // Annals of Tropical Medicine & Public Health;Jan/Feb2014, Vol. 7 Issue 1, p67 

    Splenic abscess is not an uncommon entity in tropics. In Indian subcontinent, where the incidence of enteric fever is high, abscess formation in spleen is frequently seen in clinical practice. In view of immunological functions, splenic preservation is preferred over splenectomy, especially in...

  • Dalakta Enflamatuvar Psöotüö: Olgu Sunumu. Tanrıverdi, Özgür; Sargın, Gökhan; Döğer, Fürüzan Kaçar; Meydan, Nezih; Barutca, Sabri // Medical Bulletin of Haseki / Haseki Tip Bulteni;Jun2011, Vol. 49 Issue 2, p84 

    Inflammatory pseudotumor is a benign tumor of unknown etiology and is rarely seen in the spleen. It often mimics benign and malignant tumors. The diagnosis is easily made because of the characteristic histopathological features. The most important characteristic of inflammatory pseudotumor is...

  • Comparative treatment and literature review for laparoscopic splenectomy alone versus preoperative splenic artery embolization splenectomy. Wu, Zhong; Zhou, Jin; Pankaj, Prasoon; Peng, Bing // Surgical Endoscopy;Oct2012, Vol. 26 Issue 10, p2758 

    Background: Although laparoscopic splenectomy has been gradually regarded as an acceptable therapeutic approach for patients with massive splenomegaly, intraoperative blood loss remains an important complication. In an effort to evaluate the most effective and safe treatment of splenomegaly, we...

  • Detection, Education and Management of the Asplenic or Hyposplenic Patient. Brigden, Malcolm L. // American Family Physician;02/01/2001, Vol. 63 Issue 3, p499 

    Focuses on the detection and management of asplenic or hyposplenic patients. Causative agent of infection after splenectomy; Identification of Howell-Jolly bodies on peripheral blood film as clue in asplenia or hyposplenia diagnosis; Detection of patients at risk; Medical conditions that may be...

  • Detection, Education and Management of the Asplenic or Hyposplenic Patient. Brigden, Malcolm L. // American Family Physician;2/1/2001, Vol. 63 Issue 3, p499 

    Focuses on the detection and management of asplenic or hyposplenic patients. Causative agent of infection after splenectomy; Identification of Howell-Jolly bodies on peripheral blood film as clue in asplenia or hyposplenia diagnosis; Detection of patients at risk; Medical conditions that may be...

  • Felty's syndrome: long-term follow-up after splenectomy. Moore, Rick A.; Brunner, Carolyn M.; Sandusky, William R.; Leavell, Byrd S.; Moore, R A; Brunner, C M; Sandusky, W R; Leavell, B S // Annals of Internal Medicine;Sep71, Vol. 75 Issue 3, p381 

    Presents a study which described the clinical, hematologic and serologic features, before and after splenectomy, of patients with Felty's syndrome. Method of the study; Results and discussion; Conclusion.

  • Splenic hemangiomatosis. Louis, Thomas H.; Sanders, James M.; Stephenson, Jill S.; Harbour, Lori N.; Ford III, Kenneth L. // Baylor University Medical Center Proceedings;Oct2011, Vol. 24 Issue 4, p356 

    The article presents a case report of a 56 year old woman who saw her primary care provider for progressive left flank pain with bulging of the left side of her abdomen. A discussion of diagnostic testing which was conducted on the woman, and which resulted in her receiving a diagnosis of...

  • A Cause for Conversion of Laparoscopic Splenectomy: Splenic Candidiasis. Vecchio, Rosario; Cacciola, Emma; di Martino, Marcello; Cacciola, Rossella Rosaria; MacFadyen, Bruce V. // Journal of Laparoendoscopic & Advanced Surgical Techniques;Dec2002, Vol. 12 Issue 6, p441 

    Laparoscopic splenectomy (LS) is now considered the procedure of choice for removal of the spleen in several hematologic and traumatic splenic conditions. Perisplenitis is still considered a relative contraindication. We report a rare case of isolated splenic candidiasis treated by laparoscopic...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics