Determination of higher carboxylic acids in snow samples using solid-phase extraction and LC/MS-TOF

Kippenberger, Matthias; Winterhalter, Richard; Moortgat, Geert
December 2008
Analytical & Bioanalytical Chemistry;Dec2008, Vol. 392 Issue 7/8, p1459
Academic Journal
The objective of this work was to develop a method to determine the concentrations of higher organic acids in snow samples. The target species are the homologous aliphatic α,ω-dicarboxylic acids from C5 to C13, pinonic acid, pinic acid and phthalic acid. A preconcentration procedure utilizing solid phase extraction was developed and optimized using solutions of authentic standards. The influences of different parameters such as flow rate during extraction and the concentration of the eluent on the efficiency of the extraction procedure were investigated. The compounds of interest were separated by HPLC and detected by a quadrupole time-of-flight mass spectrometer (qTOF-MS). The recovery rate (extraction efficiency) of the extraction procedure was found to vary between 41% for tridecanedioic acid and 102% for adipic acid. The limits of detection were determined for all compounds and were between 0.9 nmol/L (dodecanedioic acid) and 29.5 nmol/L (pinonic acid). An exception is pinic acid, for which a considerably higher detection limit of 103.9 nmol/L was calculated. Snow samples were collected in December 2006 and January 2007 at the Fee glacier (Switzerland) from locations at heights from 3056 to 3580 m asl and from different depths within the snow layer. In total, the analysis of 61 single snow samples was performed, and the following compounds could be quantified: homologous aliphatic α,ω-dicarboxylic acids with 5–12 carbon atoms and phthalic acid. Tridecanedioic acid, pinonic and pinic acid were identified in the samples but were not quantified due to their low concentrations. The three most abundant acids found in the molten snow samples were glutaric acid (C5-di; 3.90 nmol/L), adipic acid (C6-di; 3.35 nmol/L) and phthalic acid (Ph; 3.04 nmol/L).


Related Articles

  • Economic difficulties and bad weather stifle demand. Gibson, Jane // European Chemical News;4/11/2005, Vol. 82 Issue 2142, p12 

    Reports on the market performance of phthalic anhydride (PA) in Europe for the first quarter of 2005. Factors that contributed to the weak performance of PA in the market; Problem facing the business sector; Goal of PA producers.

  • Adipic to rise in 2006. Viswanathan, Prema // Asian Chemical News;12/5/2005, Vol. 11 Issue 517, p24 

    The article reports that adipic acid producers in Asia expect prices and margins to start increasing in 2006. Demand from the polyurethane segment is set to stage a comeback. China has been in a state of deep depression for the last few months of 2005, preventing adipic prices from climbing in...

  • Historic records of organic aerosols from a high Alpine glacier: implications of biomass burning, anthropogenic emissions, and dust transport. Müller-Tautges, C.; Eichler, A.; Schwikowski, M.; Pezzatti, G. B.; Conedera, M.; Hoffmann, T. // Atmospheric Chemistry & Physics Discussions;2015, Vol. 15 Issue 9, p13747 

    Historic records of α-dicarbonyls (glyoxal, methylglyoxal), carboxylic acids (C6-C12 dicarboxylic acids, pinic acid, p-hydroxybenzoic acid, phthalic acid, 4-methylphthalic acid), and major ions (oxalate, formate, calcium) were determined with annual resolution in an ice core from...

  • Selective Oxidation of n-Pentane Over V2O5 Supported on Hydroxyapatite. Singh, Sooboo; Jonnalagadda, Sreekanth // Catalysis Letters;Nov2008, Vol. 126 Issue 1/2, p200 

    The catalytic efficiency of V2O5 supported on hydroxyapatite in controlled oxidation of n-pentane to phthalic anhydride and maleic anhydride is investigated as function of flux rates of the reactants and temperature in the gas- phase in a fixed- bed stainless steel microreactor under steady...

  • Demand boosts PA prices. Viswanathan, Prema // Asian Chemical News;1/24/2005, Vol. 11 Issue 476, p31 

    Deals with the optimism shown by Asian phthalic anhydride (PA) producers with regard to the price increase of PA in 2005. Need for Chinese buyers to increase inventory levels; Expectation on the costs of orthoxylene.

  • Solid Phase Extraction Method for Selective Determination of Phthalate Esters in the Aquatic Environment. Fatoki, O. S.; Noma, A. // Water, Air & Soil Pollution;Oct2002, Vol. 140 Issue 1-4, p85 

    The use of solid phase extraction and capillary GLC provides the basis for the selective determination of phthalate ester plasticizers in rivers and marine water samples. Of the several solvent ratios (methanol in dichloromethane) used for selective elution of phthalate esters from the C18 solid...

  • Method validation for phthalate analysis from water. Dumitraşcu, Irina // Advances in Environmental Sciences;Jun2013, Vol. 5 Issue 2, p63 

    The goal of method validation is to provide objective evidence that the evaluated method will show acceptable reproducibility and accuracy so as to be applicable. The objective of this paper is to present a validation method for quantitative phthalates analysis from water by solid phase...

  • Novel Automated Extraction Method for Quantitative Analysis of Urinary 11 -nor-Δ9-Tetrahydrocannabinol- 9-Carboxylic Acid (THC-COOH). Shanlin Fu; Lewis, John // Journal of Analytical Toxicology;May2008, Vol. 32 Issue 4, p292 

    The article reports on the development of an automated extraction method for extracting the major urinary metabolite of cannabis on four-probe Gilson ASPEC XL4 solid-phase extraction system. The method works on liquid-liquid extraction principles but does not require the use of solid-phase...

  • Detecting and minimizing interferences in uranium oxidation states during dissolution of solid phases. Ervanne, H. // Journal of Radioanalytical & Nuclear Chemistry;May2004, Vol. 260 Issue 2, p249 

    Interferences in uranium oxidation states due to iron during acid dissolution of solid samples were studied. Hydrazine and different carboxylic acids were investigated for their suitability to minimize these interferences. Polyacrylic acid (PAA) was selected for further testing with common...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics