Solitary Langerhans cell histiocytosis orbital lesion: case report and review of the literature

Ulivieri, S.; Oliveri, G.; Filosomi, G.
October 2008
Revista Neurocirugia;2008, Vol. 19 Issue 5, p453
Academic Journal
Solitary eosinophilic granuloma is a rather benign and localized form of Langerhans's cell histiocytosis. Definitive diagnosis is made by histopathology including immunohistochemical detection of S-100, HLA-DR and CD1a antigens. We report the case of a twenty-five year old boy presented with headache and orbit's pain. A CT scan showed a left supero-lateral orbital mass with evidence of bone erosion. The different options of treatment are discussed and the literature is reviewed.


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