TITLE

MacroH2A1 knockdown effects on the Peg3 imprinted domain

PUB. DATE
January 2007
SOURCE
BMC Genomics;2007, Vol. 8, p479
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
34925189

 

Related Articles

  • Yy1 Gene Dosage Effect and Bi-Allelic Expression of Peg3. Perera, Bambarendage P. U.; Teruyama, Ryoichi; Kim, Joomyeong // PLoS ONE;Mar2015, Vol. 10 Issue 3, p1 

    In the current study, we tested the in vivo effects of Yy1 gene dosage on the Peg3 imprinted domain with various breeding schemes utilizing two sets of mutant alleles. The results indicated that a half dosage of Yy1 coincides with the up-regulation of Peg3 and Zim1, suggesting a repressor role...

  • Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted Domain. Thiaville, Michelle M.; Kim, Hana; Frey, Wesley D.; Kim, Joomyeong // PLoS ONE;Sep2013, Vol. 8 Issue 9, p1 

    The mammalian Peg3 domain harbors more than 20 evolutionarily conserved regions (ECRs) that are spread over the 250-kb genomic interval. The majority of these ECRs are marked with two histone modifications, H3K4me1 and H3K27ac, suggesting potential roles as distant regulatory elements for the...

  • Epigenetic instability of imprinted genes in human cancers. Joomyeong Kim; Bretz, Corey L.; Lee, Suman // Nucleic Acids Research;12/15/2015, Vol. 43 Issue 22, p10689 

    Many imprinted genes are often epigenetically affected in human cancers due to their functional linkage to insulin and insulin-like growth factor signaling pathways. Thus, the current study systematically characterized the epigenetic instability of imprinted genes in multiple human cancers....

  • The mouse H19 locus mediates a transition between imprinted and non-imprinted DNA replication patterns. Greally, John M.; Starr, Diana J.; Hwang, Steven; Song, Liqun; Jaarola, Maarit; Zemel, Sharon // Human Molecular Genetics;Jan1998, Vol. 7 Issue 1, p91 

    Studies the physical circumscription of the mouse chromosome 7F imprinted domain, which includes the imprinted Ins2, Igf2 and H19 genes. Effects of genomic imprinting; Asynchronous replication demonstrated by regions affected by genomic imprinting; Observation of a transition from asynchoronoud...

  • Analysis of imprinted murine Peg3 locus in transgenic mice. Szeto, Irene Y. Y.; Barton, Sheila C.; Keverne, E. B.; Surani, Azim M. // Mammalian Genome;Apr2004, Vol. 15 Issue 4, p284 

    Peg3 is an imprinted gene exclusively expressed from the paternal allele. It encodes a C2H2 type zinc-finger protein and is involved in maternal behavior. It is important for TNF-NFkB signaling and p53-mediated apoptosis. To investigate the imprinting mechanism and gene expression of Peg3 and...

  • Heat Stress Causes Aberrant DNA Methylation of H19 and Igf-2r in Mouse Blastocysts. Jia-Qiao Zhu; Jing-He Liu; Xing-Wei Liang; Bao-Zeng Xu; Yi Hou; Xing-Xu Zhao; Qing-Yuan Sun // Molecules & Cells (Springer Science & Business Media B.V.);2008, Vol. 25 Issue 2, p211 

    To gain a better understanding of the methylation imprinting changes associated with heat stress in early development, we used bisulfite sequencing and bisulfite restriction analysis to examine the DNA methylation status of imprinted genes in early embryos (blastocysts). The paternal imprinted...

  • Family way. Cohen, Philip // New Scientist;04/17/99, Vol. 162 Issue 2182, p17 

    Discusses imprinted genes in mice offspring. Mest and Peg3 genes which control the way female mice treat their young; How imprinted genes work; Suggestions as to why imprinting evolved; Study conducted on Peg3; Indications of strong evolutionary pressure for maternal behavior to be controlled...

  • Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development. Koppes, Erik; Himes, Katherine P.; Chaillet, J. Richard // PLoS ONE;8/4/2015, Vol. 10 Issue 8, p1 

    Mutations in imprinted genes or their imprint control regions (ICRs) produce changes in imprinted gene expression and distinct abnormalities in placental structure, indicating the importance of genomic imprinting to placental development. We have recently shown that a very broad spectrum of...

  • Blendas PLA/PEgAA: Avaliação da reatividade entre os polímeros e da concentração de PEgAA nas propriedades e na morfologia. de Araújo, J. P.; Agrawall, P.; de Mélo, T. J. A. // Revista Eletrônica de Materiais e Processos;2015, Vol. 10 Issue 3, p118 

    In this work, the reactivity between the polymers of PLA/PEgAA blend and the effect of PEgAA content on the properties and morphology of PLA was evaluated. The blends containing 5, 10 and 15% (wt) of PEgAA were prepared by extrusion followed by injection molding and characterized by FTIR, DSC,...

  • Molecular and DNA methylation analysis of Peg10 and Xist gene in sheep. Lixia Zhao; Gaoping Zhao; Haiyan Xi; Yiyi Liu; Kaifeng Wu; Huanmin Zhou // Molecular Biology Reports;Jun2011, Vol. 38 Issue 5, p3495 

    Peg10 is a maternally imprinted gene located in the imprinted domain of human chromosome 7q21 and mouse proximal chromosome 6. It is predominantly expressed in, and participates in the formation of, the placenta. Moreover, Peg10 is overexpressed in hepatocellular carcinoma, and is involved in...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics