TITLE

Pancreatic Expression database: a generic model for the organization, integration and mining of complex cancer datasets

PUB. DATE
January 2007
SOURCE
BMC Genomics;2007, Vol. 8, p439
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
34925168

 

Related Articles

  • Data integration and exploration for the identification of molecular mechanisms in tumor-immune cells interaction. Mlecnik, Bernhard; Sanchez-Cabo, Fatima; Pornpimol Charoentong; Bindea, Gabriela; Pagès, Franck; Berger, Anne; Galon, Jerome; Trajanoski, Zlatko // BMC Genomics;2010 Supplement 1, Vol. 11, Special section p1 

    Cancer progression is a complex process involving host-tumor interactions by multiple molecular and cellular factors of the tumor microenvironment. Tumor cells that challenge immune activity may be vulnerable to immune destruction. To address this question we have directed major efforts towards...

  • Bmi1 Enhances Tumorigenicity and Cancer Stem Cell Function in Pancreatic Adenocarcinoma. Proctor, Erica; Waghray, Meghna; Lee, Cheong Jun; Heidt, David G.; Yalamanchili, Malica; Li, Chenwei; Bednar, Filip; Simeone, Diane M. // PLoS ONE;Feb2013, Vol. 8 Issue 2, p1 

    Background: Bmi1 is an integral component of the Polycomb Repressive Complex 1 (PRC1) and is involved in the pathogenesis of multiple cancers. It also plays a key role in the functioning of endogenous stem cells and cancer stem cells. Previous work implicated a role for cancer stem cells in the...

  • Identification of key candidate genes for pancreatic cancer by bioinformatics analysis. Lv, Kui; Yang, Jianying; Sun, Junfeng; Guan, Jianguo // Experimental & Therapeutic Medicine;Jul2019, Vol. 18 Issue 1, p451 

    Although pancreatic cancer has the highest mortality rate among all neoplasms worldwide, its exact mechanism remains poorly understood. In the present study, three Gene Expression Omnibus (GEO) datasets were integrated to elucidate the potential genes and pathways that contribute to the...

  • DAPPER: a data-mining resource for protein-protein interactions. Haider, Syed; Lipinszki, Zoltan; Przewloka, Marcin R.; Ladak, Yaseen; D'Avino, Pier Paolo; Kimata, Yuu; Lio', Pietro; Glover, David M. // BioData Mining;9/24/2015, Vol. 8 Issue 1, p1 

    Background: The identification of interaction networks between proteins and complexes holds the promise of offering novel insights into the molecular mechanisms that regulate many biological processes. With increasing volumes of such datasets, especially in model organisms such as Drosophila...

  • The UCSC Genome Browser Database: update 2006. Hinrichs, A. S.; Karolchik, D.; Baertsch, R.; Barber, G. P.; Bejerano, G.; Clawson, H.; Diekhans, M.; Furey, T. S.; Harte, R. A.; Hsu, F.; Hillman-Jackson, J.; Kuhn, R. M.; Pedersen, J. S.; Pohl, A.; Raney, B. J.; Rosenbloom, K. R.; Siepel, A.; Smith, K. E.; Sugnet, C. W.; Sultan-Qurraie, A. // Nucleic Acids Research;Jan2006, Vol. 34 Issue suppl 1, pd590 

    The University of California Santa Cruz Genome Browser Database (GBD) contains sequence and annotation data for the genomes of about a dozen vertebrate species and several major model organisms. Genome annotations typically include assembly data, sequence composition, genes and gene predictions,...

  • A Generic Procedure for Integration Testing of ETL Procedures. Mekterović, Igor; Brkić, Ljiljana; Baranović, Mirta // Automatika: Journal for Control, Measurement, Electronics, Compu;2011, Vol. 52 Issue 2, p169 

    In order to attain a certain degree of confidence in the quality of the data in the data warehouse it is necessary to perform a series of tests. There are many components (and aspects) of the data warehouse that can be tested, and in this paper we focus on the ETL procedures. Due to the...

  • Integrating gene expression and epidemiological data for the discovery of genetic interactions associated with cancer risk. Bonifaci, Núria; Colas, Eva; Serra-Musach, Jordi; Karbalai, Nazanin; Brunet, Joan; Gómez, Antonio; Esteller, Manel; Fernández-Taboada, Enrique; Berenguer, Antoni; Reventós, Jaume; Müller−Myhsok, Bertram; Amundadottir, Laufey; Duell, Eric J.; Pujana, Miquel Àngel // Carcinogenesis;Mar2014, Vol. 35 Issue 3, p578 

    Dozens of common genetic variants associated with cancer risk have been identified through genome-wide association studies (GWASs). However, these variants only explain a modest fraction of the heritability of disease. The missing heritability has been attributed to several factors, among them...

  • Expressiveness and Complexity of Generic Graph Machines. Gemis, M.; Paredaens, J.; Peelman, P.; Bussche, J. Van den // Theory of Computing Systems;1998, Vol. 31 Issue 3, p231 

    The Generic Graph Machine (GGM) model is a Turing machine-like model for expressing generic computations working directly on graph structures. In this paper we present a number of observations concerning the expressiveness and complexity of GGMs. Our results comprise the following: (i) an...

  • Analysis of dysregulation of immune system in pancreatic cancer based on gene expression profile. Wang, Baosheng; Sun, Shaolong; Liu, Zhen // Molecular Biology Reports;Jul2014, Vol. 41 Issue 7, p4361 

    The aim of this study was to explore the dysregulated expression of the immune system in pancreatic cancer and clarify the pathogenesis of pancreatic cancer. The Dataset GSE15471 was downloaded from GEO database, Student's t test was used to screen differentially expressed genes (DEGs) between...

  • The pancreatic expression database: recent extensions and updates. Dayem Ullah, Abu Z.; Cutts, Rosalind J.; Ghetia, Millika; Gadaleta, Emanuela; Hahn, Stephan A.; Crnogorac-Jurcevic, Tatjana; Lemoine, Nicholas R.; Chelala, Claude // Nucleic Acids Research;Jan2014, Vol. 42 Issue D1, pD944 

    The Pancreatic Expression Database (PED, http://www.pancreasexpression.org) is the only device currently available for mining of pancreatic cancer literature data. It brings together the largest collection of multidimensional pancreatic data from the literature including genomic, proteomic,...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics