Cell polarity: Sticky poles

Heinrichs, Arianne
November 2008
Nature Reviews Molecular Cell Biology;Nov2008, Vol. 9 Issue 11, p823
Academic Journal
The article reports on PopZ, a multimeric protein in Caulobacter crescentus that anchors chromosome origins at bacterial cell poles. It states that two groups of researchers identified the popZ gene in a screen for polarity factors, and showed that cells that lack or overexpress PopZ have a cell division defect. The PopZ localizes to the existing old cell pole and later accumulates at the newly formed pole following replication initiation.


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