TITLE

Conducting polymer-based impedimetric aptamer biosensor for in situ detection

AUTHOR(S)
Wei Liao; Randall, Brad A.; Alba, Nicolas A.; Cui, Xinyan Tracy
PUB. DATE
November 2008
SOURCE
Analytical & Bioanalytical Chemistry;Nov2008, Vol. 392 Issue 5, p861
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We have successfully developed the first prototype of an electrochemical protein biosensor using polypyrrole as the substrate and doped aptamer as the probe. The sensitivity for a specific target is 10 ng/ml. Two targets, platelet-derived growth factor and immunoglobulin E, have been tested. In both cases the sensor exhibited high specificity and the signal was found to increase as the target concentration increased.
ACCESSION #
34851664

 

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