Natalizumab and PML: a risky business?

Clifford, David B.
October 2008
Gut;Oct2008, Vol. 57 Issue 10, p1347
Academic Journal
The article discusses the development of treatments including natalizumab (Tysabri), a drug used to treat Crohn's disease. It cites that the drug is a humanized monoclonal antibody against 4-integrin, which is first approved for treatment on relapsing multiple sclerosis (MS). It contends that this drug minimizes the activity of MS as shown by the development of magnetic resonance (MR) brain lesions and slowing progression of disability.


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