TITLE

Presentation of stable angina pectoris among women and South Asian people

AUTHOR(S)
Zaman, M. Justin; Junghans, Cornelia; Sekhri, Neha; Chen, Ruoling; Feder, Gene S.; Timmis, Adam D.; Hemingway, Harry
PUB. DATE
September 2008
SOURCE
CMAJ: Canadian Medical Association Journal;9/23/2008, Vol. 179 Issue 7, p659
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: There is speculation that women and South Asian people are more likely than men and white people to report atypical angina and that they are less likely to undergo invasive management of angina. We sought to determine whether atypical symptoms of angina pectoris in women and South Asians impacted clinically important outcomes and clinical management. Methods: We prospectively identified 2189 South Asian people and 5605 white people with recent-onset chest pain at 6 chest-pain clinics in the United Kingdom. We documented hospital admissions for acute coronary syndromes, coronary deaths as well as coronary angiography and revascularization procedures. Results: Atypical chest pain was reported by more women than men (56.5% vs 54.5%, p < 0.054) and by more South Asian patients than white patients (59.9% vs 52.5%, p < 0.001). Typical symptoms were associated with coronary death or acute coronary syndromes among women (hazard ratio [HR] 2.30, 95% CI 1.70—3.11, p < 0.001) but not among men (HR 1.23, 95% CI 0.96—1.57, p = 0.10). Typical symptoms were associated with coronary outcomes in both South Asian and white patients. Among those with typical symptoms, women (HR 0.76, 95% CI 0.63—0.92, p = 0.004) and South Asian patients (HR 0.52, 95% CI 0.41—0.67, p < 0.001) were less likely than men and white patients to receive angiography. Interpretation: Compared to those with atypical chest pain, women and South Asian patients with typical pain had worse clinical outcomes. However, sex and ethnic background did not explain differences in the use of invasive procedures.
ACCESSION #
34283301

 

Related Articles

  • Exercise Tests in Patients With Severe Angina Pectoris: An Angiographic Correlation. Eshchar, Y.; Yahini, J. H.; Atlas, P.; Kishon, Y.; Deutsch, V.; Neufeld, H. N. // Angiology;Jan1980, Vol. 31 Issue 1, p32 

    Graded submaximal ergometric tests were performed on 60 patients who suffered from clinically severe angina pectoris, and the results were correlated with their coronary angiograms. The test was positive in 44, negative in 9, and undetermined in 7 patients (defined as failure to reach the...

  • SINGLE CORONARY ARTERY WITH ISCHEMIA AND SUDDEN CARDIAC ARREST. Kongkiat Chaikriangkrai; Kassi, Mahwash; Polsani, Venkateshwar; Su Min Chang // Methodist DeBakey Cardiovascular Journal;Apr-Jun2014, Vol. 10 Issue 2, p121 

    Single coronary artery (SCA) is a very rare finding. Although most cases of SCA are found incidentally on coronary angiography, it can potentially lead to different clinical repercussions.1, 2 Herein we describe a patient with SCA who had unstable angina with subsequent sudden cardiac arrest,...

  • Poster display IV experimental and instrumentation. Masoli, O.; Redruello, M.; Ogresta, F.; Collaud, C.; Koslowski, P.; Baliño, N.; Eleta, M.; Arce, P.; Vidal, L.; Kardash, O.; Maroz-Vadalajskaya, N.; Vanhove, C.; Lahoutte, T.; Defrise, M.; Andreyev, A.; Bossuyt, A.; Franken, P.; Maskali, F.; Nloga, J.; Tran, N. // Journal of Nuclear Cardiology;Mar2005, Vol. 12 Issue 2, pS60 

    The article presents abstracts on topics related to nuclear cardiology, including the diagnostic value of transthoracic ultrasound in assessing distal graft anastamosispatency, assessing the presence of ischemia in postmenopausal women with angina using normal coronary angiograms and the impact...

  • Non-invasive decision making in stable angina. Meune, C.; Aïssou, L.; Pop, N.; Goudot, F.-X.; Schaap, Jeroen; de Groot, Joris A. H.; Nieman, Koen; Meijboom, W Bob; Boekholdt, S Matthijs; Post, Martijn C.; Van der Heyden, Jan A.; de Kroon, Thom L.; Rensing, Benno J. W. M.; Moons, Karel G. M.; Verzijlbergen, J Fred // Heart;Aug2013, Vol. 99 Issue 15, p1136 

    A letter to the editor is presented in response to the article "Hybrid myocardial perfusion SPECT/CT coronary angiography and invasive coronary angiography in patients with stable angina pectoris lead to similar treatment decision" that was published in the previous issue.

  • Clinical features, risk factors, and referral delay in British patients of Indian and European origin with angina matched for age and extent of coronary atheroma. Shaukat, Nateem; de Bono, D.P.; Cruickshank, J.K. // BMJ: British Medical Journal (International Edition);9/18/93, Vol. 307 Issue 6906, p717 

    Compares the clinical features and risk factors in patients of Indian origin and white patients with angina in Great Britain. Diagnosis by coronary angiography; Association of Indian origin with an increased risk of coronary disease; Variability of symptom onset to consultation in Indian group.

  • Brief episode of ischemia activates protective genetic program in rat heart: a gene chip study Simkhovich, Boris Z.; Marjoram, Paul; Poizat, Coralie; Kedes, Larry; Kloner, Robert A. // Cardiovascular Research;Aug2003, Vol. 59 Issue 2, p450 

    Objective: Brief episodes of ischemia of 20 min or less have the potential to protect the heart. Such episodes are associated primarily with reversible ischemic injury yet they induce changes in gene expression. The purpose of the study was to determine whether activation of protective...

  • Comparison of Silent and Symptomatic Ischemia during Exercise Testing in Men. Miranda, Cres P.; Lehmann, Kenneth G.; Lachterman, Bruce; Coodley, Eugene M.; Froelicher, Victor F. // Annals of Internal Medicine;4/15/91, Vol. 114 Issue 8, p649 

    Presents a study which compared angina and silent ischemia-segment depression during exercise testing. Methodology; Results; Discussion.

  • Chest pain puzzle. Bachman, William R.; Cohen, Mylan C. // Cortlandt Forum;6/25/96, Vol. 9 Issue 6, p170 

    Presents an analysis of a medical case involving the difficulty of treating a 69-year-old woman due to her inability to give an accurate medical history of her cardiac illness and extreme obesity. Limited of her clinical examinations due to her size; Symptoms of ischemic coronary disease;...

  • CORONARY ARTERY DISEASE IN SOUTH ASIAN IMMIGRANTS LIVING IN NEW YORK CITY: ANGIOGRAPHIC FINDINGS AND RISK FACTOR BURDENS. Silbiger, Jeffrey J.; Stein, Russell; Roy, Monisankar; Nair, Murali K.; Cohen, Pilar; Shaffer, Jonathan; Pinkhasov, Arthur; Kamran, Mazullah // Ethnicity & Disease;Summer2013, Vol. 23 Issue 3, p292 

    Background: The prevalence of coronary artery disease (CAD) among South Asians (SAs) significantly exceeds that of Caucasians. South Asians also suffer from more premature, clinically aggressive and angiographically extensive (3-vessel) disease. The role of conventional CAD risk factors (CCRFs)...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics