TITLE

Novel epidemiological features of moyamoya disease

AUTHOR(S)
Baba, T; Houkin, K; Kuroda, S
PUB. DATE
August 2008
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Aug2008, Vol. 79 Issue 8, p900
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Many clinical features that are specific t~ moyamoya disease have been reported and cited in textbooks based on previous data. The purpose of this study is to investigate the present epidemiological features of moyamoya disease based on recently obtaine regional all-inclusive data. Methods: The authors performed an all-inclusive surve of moyamoya disease in Hokkaido, one of the major islands in Japan that has a population of 5.63 million. Th epidemiological features were analysed based on the dat from 267 newly registered patients with moyamoya disease in Hokkaido from 2002 to 2006. These analyse data were adjusted to the whole Japanese population a 2005. Results: The detection rate of the disease per year was 0.94 patients per 100 000 people, and prevalence was 10.5 patients per 100 000 people. The incidence of ischaemia concerned with the disease was 0.53 patients per 100 000 people-years and haemorrhage was 0.2 patients per 100 000 people-years The ratio of female to male patients was 2.18. The ratio a patients aged 10 years and above to under 10 years of age at onset was 6.18. Two peaks for age of onset wen seen: the highest was observed between 45 and 49 years, and the second between 5 and 9 years. Asymptomatic patients comprised 17.8% of the total number of patients. Conclusion: The epidemiological features of moyamoya disease determined by this survey varied considerably from previous data. The detection rate and prevalence a the disease were higher than those reported previously. The highest peak of onset age was older than those reported previously. In addition, it was revealed that asymptomatic moyamoya patients are not always rare ii Japan.
ACCESSION #
34263911

 

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