TITLE

Germline MC1R Variants and BRAF Mutant Melanoma

AUTHOR(S)
Hacker, Elke; Hayward, Nicholas K
PUB. DATE
October 2008
SOURCE
Journal of Investigative Dermatology;Oct2008, Vol. 128 Issue 10, p2354
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between MC1R and BRAF in different melanoma subtypes.Journal of Investigative Dermatology (2008) 128, 2354–2356. doi:10.1038/jid.2008.236
ACCESSION #
34251512

 

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