TITLE

Seroprevalence of human immunodeficiency virus in Nepalese blood donors: A study from three regional blood transfusion services

AUTHOR(S)
Tiwari, Bishnu Raj; Ghimire, Prakash; Karki, Surendra; Rajkarnikar, Manita
PUB. DATE
July 2008
SOURCE
Asian Journal of Transfusion Science;Jul-Dec2008, Vol. 2 Issue 2, p66
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background and Objective: The likelihood of human immunodeficiency virus (HIV) infection occurring in recipients of HIV seropositive blood is close to 100%. Transmission during window period is still possible even each unit of blood is tested for anti-HIV 1 and 2 antibodies. The possibility of window period transmission would be minimized if blood is collected from low risk targeted general public. A continuous surveillance data might prove valuable for concerned authorities to assess their service and plan for further improvements in transfusion safety. Our aim was to determine the seroprevalence of HIV in regional blood transfusion services located at three developmental regions of Nepal and compare the results. Materials and Methods: A total of 16,557 blood donors were screened for anti-HIV 1 and 2 antibodies in three blood transfusion services viz. 5,351 donors in Morang, 5,211 in Banke, 5,995 in Kaski by using rapid anti HIV 1 and 2 Test. The statistical significance of difference in seroprevalence was tested by Fisher's Exact Test using the statistical software 'Winpepi ver 3.8'. Results: The overall seroprevalence of HIV among blood donors in the regional blood transfusion services was 0.054% (9/16557) and 100% seropositivity was among male donors. The individual seroprevalence in Morang was 0.019%, in Banke was 0.095% and in Kaski was 0.05%. The HIV seroprevalence was not significantly different in regional blood transfusion services of Nepal (Fisher Exact Test, P = 0.2096). Conclusion: The seroprevalence in the regional blood transfusion service of Nepal was quite low and the seroprevalence rate was not significantly different.
ACCESSION #
34232853

 

Related Articles

  • HIV SEROPOSITIVITY IN HUSM BLOOD DONORS. M. N., Noor Haslina; B., Rosnah; M. Y., Shafini; W. M., Wan Haslinda // Malaysian Journal of Medical Sciences;Jan2006 Supplement, Vol. 13, p212 

    PURPOSE : Transfusion of HIV continues to be a threat to safe blood transfusion. Developing countries account for more than 90% of all new HIV cases. In Malaysia the number of infected individuals has increased steadily each year. The objective of this study is to assess the prevalence and trend...

  • Calculations.  // Canadian Nurse;Jun2011, Vol. 107 Issue 6, p10 

    Statistics related to the World Blood Donor Day celebrated on June 14 are presented including the percentage of Canadians who state they or their families have required blood or blood products, the number of lives each person can save or improve, and the number of people who have been infected...

  • High Incidence of Transfusion-Related HIV Infection in Nigeria. Ubesie, A. C.; Emodi, I. J.; Ikefuna, A. N. // Internet Journal of Hematology;2010, Vol. 7 Issue 1, p2 

    There is a high incidence of transfusion related HIV infection in Nigeria. This was evident in our pilot study that indicated that the incidence was 1.2% in a teaching hospital in Enugu. In this article, we discuss several possible reasons for the high incidence of transfusion related HIV...

  • Transfusion in sub-Saharan Africa: does a Western model fit? Field, Stephen P.; Allain, Jean-Pierre // Journal of Clinical Pathology;Oct2007, Vol. 60 Issue 10, p1073 

    This review examines the current state of transfusion services sub-Saharan Africa and presents the argument for and against the Western model of a centralised blood service with 100% voluntary non-remunerated blood donors as advocated by the World Health Organization. The current practice of...

  • External Financial Aid to Blood Transfusion Services in Sub-Saharan Africa: A Need for Reflection. Ala, Fereydoun; Allain, Jean-Pierre; Bates, Imelda; Boukef, Kamel; Boulton, Frank; Brandfu, James; Dax, Elizabeth M.; Ekiaby, Magdy El; Farrugia, Albert; Gorlin, Jed; Hassal, Gorlin; Lee, Helen; Loua, André; Maitland, Kathryn; Mbanya, Dora; Mukhtar, Zainab; Murphy, William; Opare-Sem, Ohene; Owusu-Ofori, Shirley; Reesink, Henk // PLoS Medicine;Sep2012, Vol. 9 Issue 9, p1 

    The article discusses the impact of financial aid given by high-income countries in the North to blood transfusion services to the HIV epidemic in Sub-Saharan Africa. It has been informed that aid has resulted in unintended but serious negative outcomes as it was misdirected in areas of donor...

  • HIV Transmission Through Transfusion -- Missouri and Colorado, 2008. Lafoon, B.; Crutchield, A.; Levi, M.; Bower, W. A.; Kuehnert, M.; Brooks, J. T.; Selik, R. M.; Switzer, W. M.; Heneine, W.; Shankar, A.; Iuliano, A. D. // MMWR: Morbidity & Mortality Weekly Report;10/22/2010, Vol. 59 Issue 41, p1335 

    The article presents case reports of transfusion-transmitted HIV in HIV-infected transfusion recipients in Missouri and Colorado in 2008. The blood donating history and sex practice of the donor is presented. The result of the serum test done on a recipient in Missouri is presented. Information...

  • Blood transfusions and risk of HIV transmission.  // American Family Physician;6/1/1996, Vol. 53 Issue 8, p2713 

    Reports on a study by E.M. Lackritz, et al published in the `New England Journal of Medicine' which examined data on HIV incidence among blood donors in the United States. Estimated risk of HIV transmission through one screen blood donation.

  • Trend of transfusion transmitted infections frequency in blood donors: provide a road map for its prevention and control.  // Journal of Translational Medicine;2012, Vol. 10 Issue 1, p20 

    The article offers information on the study conducted by the authors related to the trend of transmitting infections through transfusion of blood by blood donors. It states that transfusion transmitted infections create significant burden on health care system. Donor selection is of paramount...

  • Transfusion-associated HIV infection in Mexico related to paid blood donors; HIV epidemic. Volkow, Patricia; Velasco, Silvia Ruiz; Mueller, Nancy; Ponce de Leon, Samuel; Sierra-Madero, Juan Gerardo; Sada, Eduardo; Soto, José Luis; Perez-Ancona, Franz; Ruiz-Palacios, Guillermo; Castillo, José Ramón; Mohar, Alejandro // International Journal of STD & AIDS;May2004, Vol. 15 Issue 5, p337 

    The objective of the study was to describe the clinical, epidemiological profile and conditional incubation period in a group of transfusion-associated HIV-infected (TAHI) patients seen in five national tertiary care centres in Mexico from 1983 to April 1998. Date of transfusions, AIDS...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics