The Use of Bone Morphogenetic Protein in Lumbar Spine Surgery

Rihn, Jeffrey A.; Gates, Charley; Glassman, Steven D.; Phillips, Frank M.; Schwender, James D.; Albert, Todd J.
September 2008
Journal of Bone & Joint Surgery, American Volume;Sep2008, Vol. 90-A Issue 9, p2014
Academic Journal
The article presents an overview of the use of bone morphogenetic proteins in lumbar spine surgery. A discussion of the 1965 discovery of the proteins, which are a group of growth factor proteins within a particular transforming growth factor, is presented. The history of the use of biologics in lumbar fusion surgery since 1908, including morphogenetic proteins, is discussed.


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