TITLE

Low Proportion of Barrett's Esophagus in Asian Americans

AUTHOR(S)
Lam, Khoa D.; Phan, Jeanine T.; Garcia, Ruel T.; Trinh, Huy; Nguyen, Huy; Nguyen, Khanh; Triadafilopoulos, George; Vutien, Philip; Nguyen, Long; Nguyen, Mindie H.
PUB. DATE
July 2008
SOURCE
American Journal of Gastroenterology;Jul2008, Vol. 103 Issue 7, p1625
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVES: To determine the proportion of Barrett's esophagus (BE) in Asians versus non-Asians and the predictors of BE in patients with upper gastrointestinal (GI) symptoms. METHODS: We performed a cross-sectional study to determine the proportion of BE from all consecutive patients who underwent esophagogastroduodenoscopy (EGD) for various indications at an outpatient, community-based gastroenterology practice in northern California from February 2000 to September 2006. BE was defined as endoscopically recognized presence of salmon-pink mucosa in the distal esophagus and intestinal metaplasia on biopsy. We also performed a nested case–control study to determine potential predictors of BE. RESULTS: In total, 5,293 patients were reviewed. BE was more common in non-Asians (31/1464, 2.1%) than Asians (29/3829, 0.76%) ( P < 0.001). In multivariate analysis controlling for increasing age, male gender, ethnicity, smoking, and alcohol, the strongest predictor of the presence of BE was non-Asian ethnicity (odds ratio [OR] 3.55, 95% confidence interval [CI] 1.85–6.85), followed by male gender (OR 2.68, 95% CI 1.32–5.45). CONCLUSION: BE is uncommon in Asian Americans; non-Asian ethnicity and male gender are significant independent predictors of BE.
ACCESSION #
34184626

 

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