Short-term associations between fine and coarse particles and hospital admissions for cardiorespiratory diseases in six French cities

Host, S.; Larrieu, S.; Pascal, L.; Blanchard, M.; Declercq, C.; Fabre, P.; Jusot, J.-F.; Chardon, B.; Le Tertre, A.; Wagner, V.; Prouvost, H.; Lefranc2, A.
August 2008
Occupational & Environmental Medicine;Aug2008, Vol. 65 Issue 8, p544
Academic Journal
Objectives: Little is known about the potential health effects of the coarse fraction of ambient particles. The aim of this study is to estimate the links between fine (PM2.5) and coarse particle (PM2.5-10) levels and cardiorespiratory hospitalisations in six French cities during 2000-2003. Methods: Data on the daily numbers of hospitalisations for respiratory, cardiovascular, cardiac and ischaemic heart diseases were collected. Associations between exposure indicators and hospitalisations were estimated in each city using a Poisson regression model, controlling for confounding factors (seasons, days of the week, holidays, influenza epidemics, pollen counts, temperature) and temporal trends. City-specific findings were combined to obtain excess relative risks (ERRs) associated with a 10 µg/m³ increase in PM2.5 and PM2.5-10 levels. Results: We found positive associations between indicators of particulate pollution and hospitalisations for respiratory infection, with an ERR of 4.4% (95% Cl 0.9 to 8.0) for PM2.5-10 and 2.5% (95% Cl 0.1 to 4.8) for PM2.5. Concerning respiratory diseases, no association was observed with PM2.5, whereas positive trends were found with PM2.5-10, with a significant association for the 0-14-year-old age group (ERR 6.2%, 95% Cl 0.4 to 12.3). Concerning cardiovascular diseases, positive associations were observed between PM2.5 levels and each indicator, although some did not reach significance; trends with PM2.5-10 were weaker and non-significant except for ischaemic heart disease in the elderly (ERR 6.4%, 95% Cl 1.6 to 11.4). Conclusions: In accordance with other studies, our results indicate that the coarse fraction may have a stronger effect than the fine fraction on some morbidity endpoints, especially respiratory diseases.


Related Articles

  • Are fine or coarse particles responsible for the effects of air pollution? Loomis, Dana // Occupational & Environmental Medicine;Aug2008, Vol. 65 Issue 8, p505 

    The article presents a study on whether coarse or fine particles are responsible for the effects of air pollution in France. The short-term associations of hospital admissions with particle concentrations in 6 French cities are studied. It shows that coarse particles were more strongly related...

  • Flu shots could cut cardiac hospital stays.  // Healthcare Purchasing News;May2003, Vol. 27 Issue 5, p6 

    Presents the result of a survey on the effect of flu vaccinations on the hospital stays of heart disease patients in the U.S. Background of the study; Decline in hospital stays for stroke; Views of physician William Schaffner on the research.

  • Almanac 2013: heart failure. Clark, Andrew L. // Romanian Journal of Cardiology;2013, Vol. 23 Issue 4, p348 

    The article offers updates related to heart failure. The National Heart Failure Audit is still an invaluable resource for understanding how acute heart failure is managed in England and Wales. Patients with chronic stable heart failure have been a focus for heart failure research. Half of...

  • Low-Level Air Pollution and Hospital Admissions for Cardiac and Cerebrovascular Diseases in Helsinki. Pönkä, Antti; Virtanen, Mikko // American Journal of Public Health;Sep96, Vol. 86 Issue 9, p1273 

    Objectives. This study investigated whether low concentrations of ambient air pollutants are associated with hospital admissions for ischemic cardiac and cerebrovascular diseases. Methods. Associations between daily concentrations of sulfur dioxide, nitric oxide, nitrogen dioxide, ozone, and...

  • Air pollution and cardiovascular admissions association in Spain: results within the EMECAS project. Ballester, F.; Rodríguez, P.; Iñíguez, C.; Saez, M.; Daponte, A.; Galán, I.; Taracido, M.; Arribas, F.; Bellido, J.; Cirarda, F. B.; Cañada, A.; Guillén, J. J.; Guillén-Grima, F.; López, E.; Pérez-Hoyos, S.; Lertxundi, A.; Toro, S. // Journal of Epidemiology & Community Health;Apr2006, Vol. 60 Issue 4, p328 

    Objective: To evaluate the short term effect of air pollution on cardiovascular admissions in 14 Spanish cities Methods: The period under study was from 1995 to 1999. Daily emergency admissions for all cardiovascular diseases (CVD) and heart diseases (HD) were obtained from hospital records, and...

  • Use of Twice-Daily Exenatide in Basal Insulin--Treated Patients With Type 2 Diabetes. Buse, John B.; Bergenstal, Richard M.; Glass, Leonard C.; Heilmann, Cory R.; Lewis, Michelle S.; Kwan, Anita Y. M.; Hoogwerf, Byron J.; Rosenstock, Julio // Annals of Internal Medicine;1/18/2011, Vol. 154 Issue 2, p103 

    Background: Insulin replacement in diabetes often requires prandial intervention to reach hemoglobin A1c (HbA1c) targets. Objective: To test whether twice-daily exenatide injections reduce HbA1c levels more than placebo in people receiving insulin glargine. Design: Parallel, randomized,...

  • Adult Congenital Heart Disease. Moodie, Douglas // Texas Heart Institute Journal;2011, Vol. 38 Issue 6, p705 

    The article presents a study which looks into hospital admissions of over 84,000 adult congenital heart disease (CHD) in 2007 in the U.S. The study discovers several comorbidities of CHD including arrhythmias, pulmonary hypertension, and renal failure. It concludes that there is insufficient...

  • Intermittent Outpatient Nesiritide Infusion Reduces Hospital Admissions in Patients With Advanced Heart Failure. Schwarz, Ernst R.; Najam, Sabeen; Akel, Rami; Sulimanjee, Nasir; Bionat, Susan; Rosanio, Salvatore // Journal of Cardiovascular Pharmacology & Therapeutics;Sep2007, Vol. 12 Issue 3, p232 

    This article discusses findings of a study, which evaluated the effect of intermittent outpatient nesiritide infusion on hospital readmission rate and symptoms as well as renal function. In this study, patients with decompensated heart failure were recruited for intermittent outpatient...

  • The Reliability of Racial Classifications in Hospital Discharge Abstract Data. Blustein, Jan // American Journal of Public Health;Jun94, Vol. 84 Issue 6, p1018 

    Many studies demonstrating an association between race and the use of medical services have used hospital discharge abstract data. The quality of the measures of race in such data sources has here to force been unexplored. Hospital discharge abstract data from New York State were used to...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics