A cystic amelanotic melanoma metastasis to the brain: case report

Cemil, B.; Emmez, H.; Oztanır, N.; Tokgoz, N.; Dogulu, F.
August 2008
Revista Neurocirugia;2008, Vol. 19 Issue 4, p365
Academic Journal
As far as we know, cyst formation in intracranial melanoma is rare, and only 15 cases of intracranial amelanotic melanoma have been reported until now. A yellowish mass was observed in the frontal lobe. The content of the cyst consisted of old hematoma, xanthochromic fluid and necrotic tissue, was evacuated and the cyst wall was totally resected. No abnormal pigmentation was noted in the cyst wall and surrounding brain tissue. The imaging features of metastatic melanomas are distinctive due to the presence of melanin and the propensity for hemorrhage. Both hemorrhage and melanin can produce T1-weighted hyperintensity and T2-weighted signal intensity loss.


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