TITLE

Lower dose of temsirolimus as effective for treating mantle cell lymphoma as higher dose

PUB. DATE
September 2008
SOURCE
Hem/Onc Today;9/10/2008, Vol. 9 Issue 16, p24
SOURCE TYPE
Newspaper
DOC. TYPE
Article
ABSTRACT
The article discusses research being done on the use of temsirolimus in treating mantle cell lymphoma. It references a study which appeared in the 2008 issue of "Cancer." In the study, patients with relapse or refractory mantle cell lymphoma who had previously received treatment were assigned to receive weekly doses of 25 milligram (mg) intravenous (IV) temsirolimus for 6 four-week cycles. Research revealed overall response rate of 41%.
ACCESSION #
34154550

 

Related Articles

  • DESIGN AND CHARACTERIZATION OF MODIFIED RELEASE ISONIAZID AND SALBUTAMOL SULPHATE INLAY TABLET. Prasad, M. Sarat Chandra; Babu, B. Nagendra; Ajay, M.; Raj, S. Brito; Audinarayana, N.; Reddy, K. Bhaskar // International Journal of Pharmacy & Pharmaceutical Sciences;Oct2011, Vol. 3 Issue 4, p153 

    The objective of the present study was to improve the therapeutic efficacy of a formulation which contains two drugs i.e. Isoniazid and Salbutamol sulphate. The present invention is to provide a dosage form comprising of an active ingredient (Isoniazid) as modified release and another active...

  • Assessment of tracheal intubation in adults after induction with sevoflurane and different doses of propofol: a randomly controlled trial. Ping Li; LinLi Luo; Jian Wang; Wei Huang // International Journal of Clinical & Experimental Medicine;2015, Vol. 8 Issue 8, p14042 

    Intubation without prior administration of muscle relaxants is a common practice in children and adults with potential difficult airways. We aimed to investigate the effects of adding different doses of propofol on tracheal intubation and the time to return of spontaneous breathing during...

  • Three-pronged treatment well tolerated in patients with indolent lymphomas. Forman, Stephen; Adams, Stacey L.; Dickinson, Cara; Levitan, Dave; Shafer, Emily // Hem/Onc Today;4/10/2008, Vol. 9 Issue 6, p39 

    This article focuses on a study published in a 2008 issue of "Leukemia & Lymphoma" that examined the effectiveness of fludarabine, mitoxantrone and rituximab as a three-pronged treatment regimen for patients with indolent lymphomas. Particular focus is given to the dosing regimen received by the...

  • USE OF PENICILLIN AS A ROOT CANAL TREATMENT. BUCHBINDER, MAURICE // Journal of Dental Research;Feb1946, Vol. 25 Issue 1, p13 

    The article presents a study examining the usage of penicillin to treat root canal infections. Topics researched by the study are mentioned, including the questions of the sensitivity of root canal organisms to penicillin, the dosage that can safely be given to patients, and the best method for...

  • Identification of the Rate-Determining Process in the Hepatic Clearance of Atorvastatin in a Clinical Cassette Microdosing Study. Maeda, K.; Ikeda, Y.; Fujita, T.; Yoshida, K.; Azuma, Y.; Haruyama, Y.; Yamane, N.; Kumagai, Y.; Sugiyama, Y. // Clinical Pharmacology & Therapeutics;Oct2011, Vol. 90 Issue 4, p575 

    Clearance of atorvastatin occurs through hepatic uptake by organic anion transporting polypeptides (OATPs) and subsequent metabolism by cytochrome P450 (CYP) 3A4. To demonstrate the relative importance of OATPs and CYP3A4 in the hepatic elimination of atorvastatin in vivo, a clinical cassette...

  • New drugs and dosage forms.  // American Journal of Health-System Pharmacy;4/15/2005, Vol. 62 Issue 8, p790 

    The article informs about some new drugs and dosage forms. It informs about desloratidine and pseudoephedrine sulfate extended-release tablets. The product is indicated for the relief of nasal congestion and other symptoms of seasonal rhinitis in patients age 12 years or older. Use of the...

  • Particle Size Determination in Pharmaceutical Applications.  // LabAsia;2011, Vol. 18 Issue 1, p22 

    The article focuses on the importance of the particle size of dosage forms in the efficacy of the drug.

  • FAST DISSOLVING ORAL FILMS: A NOVEL DRUG DELIVERY SYSTEM FOR DICLOFENAC. Kumar, S. Naveen; Agilandeswari, D.; Sabitha, P.; Prathyusha, A.; Yathiraju, K.; Chandy, Vineeth // Pharma Science Monitor;Jan2013, Vol. 4 Issue 1, p3649 

    Fast Dissolving Films (FSF's) are the most advanced form of oral solid dosage form due to more flexibility and comfort. It improves the efficacy of the API's by dissolving within a minute in oral cavity after the contact with less saliva as compared to Fast Dissolving Tablets (FDT's), without...

  • Conversion of Nanosuspensions into Dry Powders by Spray Drying: A Case Study. Mahesh Chaubal // Pharmaceutical Research;Oct2008, Vol. 25 Issue 10, p2302 

    Abstract Purpose  Drying of nanosuspensions can cause destabilization of the particles, leading to irreversible aggregation. In order to prepare an effective solid dosage form for a nanosuspension, it is imperative that the spray-dried nanoparticles should go back to their original...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics