TITLE

Gene modulation and severity of lung disease in cystic fibrosis

AUTHOR(S)
Pillai, A
PUB. DATE
August 2008
SOURCE
Thorax;Aug2008, Vol. 63 Issue 8, p670
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses a study which shows that children with cystic fibrosis with mannose binding lectin 2 (MBL2) deficiency acquired Pseudomonas infection earlier and also had a faster rate of decline in lung function than those with intermediate or high levels of MBL2. It emphasizes the need for further studies in evaluating the effects of other pulmonary modifiers and their interactions in what is an increasingly complex genetic disease.
ACCESSION #
34153255

 

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