Chronic vulvocrural dermatitis with burning and itching

Le Donne, Maria; Lentini, Maria; Moretti, Giovanna; Cannavò, Serafinella Patrizia
September 2008
CMAJ: Canadian Medical Association Journal;9/9/2008, Vol. 179 Issue 6, p555
Academic Journal
The article offers information on Hailey-Hailey disease or familial benign pemphigus. Hailey-Hailey disease is an autosomal dominant disorder characterized on chromosome as mutation in the adenosine triphosphate gene. Study shows that about 15% of patients with Hailey-Hailey disease do not have history of the disease because of a sporadic gene mutation. Hailey-Hailey disease is frequently misdiagnosed as eczema or bacterial or fungal infection because of its temporary responses to topical corticosteroids combined with antibiotics or antifungal agents. The disease can be treated with photodynamic therapy, electrodessication, and cryosurgery. Meanwhile, a case study of a 73-year-old woman with Hailey-Hailey disease is presented.


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