TITLE

Symbiotic containing Bifidobacterium animalis and inulin increases stool frequency in elderly healthy people

AUTHOR(S)
Franz Zunft, H.-J.; Hanisch, C.; Mueller, S.; Koebnick, C.; Blaut, M.; Doré, J.
PUB. DATE
June 2004
SOURCE
Asia Pacific Journal of Clinical Nutrition;2004 Supplement, Vol. 13, pS112
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: the aim of the study was to investigate the effect of a symbiotic on gut microbiota and bowel habits. Methods: a double-blind, placebo-controlled, randomized crossover study was conducted in healthy elderly people (n= 49; mean age 70 ± 4 years) over a total of sixteen weeks divided into periods of 4 weeks each, (1) run-in, (2) first intervention, (3) wash-out, and (4) second intervention. During the intervention periods study participants consumed daily sachets either containing the symbiotic or a placebo. The symbiotic contained bifidobacterium animalis and inulin. During the study subjects regularly completed questionnaires on bowel habits, well-being, gastrointestinal quality of life and underwent a medical examination. At the end of each intervention period the volunteers reported their dietary intake using a 4-day food record and provided a fresh faecal sample for the analysis of microbial and other parameters. Results: the habitual dietary intake remained constant over the entire period of investigation. The consumption of the symbiotic resulted in a significant increase of stool frequency compared to the placebo period (8.8 vs. 8.1 stools per week; p<0.05). Among other gastrointestinal symptoms, eg. Bloating, flatulence, no differences between the treatment and placebo periods could be found. For several parameters of well-being a significant positive influence of the symbiotic treatment could be demonstrated. The characterization of the microbial composition using fluorescence in-situ hybridization and enzymatic analyses are in progress. Conclusion: the administration of a symbiotic consisting of bifidobacterium animalis and inulin improves well-being and gastrointestinal quality of life in elderly subjects.
ACCESSION #
34013592

 

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