2008 - Low-dose hydrocortisone did not improve survival in patients with septic shock but reversed shock earlier

Lamontagne, Francois; Meade, Maureen O.
June 2008
ACP Journal Club;6/20/2008, Vol. 148 Issue 4, p5
Academic Journal
The article discusses whether low-dose hydrocortisone is effective and safe for septic shock. It was found in clinical trials that hydrocortisone did not differ from placebo for death at any time point. It is concluded that in septic shock, low-dose hydrocortisone shortened time to shock reversal but did not increase survival or shock reversal and increased complications. Response to corticotropin testing did not influence treatment effect.


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