TITLE

Kinomics

AUTHOR(S)
Gomase, Virendra S.; Tagore, Somnath
PUB. DATE
March 2008
SOURCE
Current Drug Metabolism;Mar2008, Vol. 9 Issue 3, p255
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Kinomics is derived from the word kinome that is the kinase part of the proteome. Kinomics is a merger between genomics and proteomics. Defining the kinase complement of the human genome, the kinome, has provided an excellent starting point for understanding the scale of the problem. This approach combines the understanding of small molecules and targets, and thereby assists the researcher in finding new targets for existing molecules or understanding selectivity and poly-pharmacology of molecules in related targets. Deciphering the complex network of phosphorylation-based signaling is necessary for a thorough and therapeutically applicable understanding of the functioning of a cell in physiological and pathological states.
ACCESSION #
33651078

 

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