Encore developing product to treat stroke and TBI

July 2008
Cardiovascular Devices & Drugs;Jul2008, Vol. 14 Issue 7, p17
The article reports on a proprietary nano-emulsion intravenous formulation of progesterone developed by Encore Therapeutics (ETI) for the treatment of stroke and traumatic brain injury (TBI) in 2008. The company is looking for a partner to introduce the ETI-411 progesterone formulation in the market. Doctor Andrew Chen, inventor of such formulation, called ETI-411 as a substantial enhancement over the current method of delivering intravenous (IV) progesterone.


Related Articles

  • Product Update.  // Journal of Psychosocial Nursing & Mental Health Services;Oct2013, Vol. 51 Issue 10, p6 

    No abstract available.

  • OTHER NEWS TO NOTE.  // BioWorld Today;6/25/2008, Vol. 19 Issue 123, p2 

    This section offers news briefs on the U.S. biopharmaceutical industry as of June 25, 2008. Encore Therapeutics Inc. has revealed the creation of a nano-emulsion intravenous formulation of progesterone for the treatment of stroke and brain injury. GeNOsys Inc. and the University of British...

  • Progesterone and TBI: Encore Therapeutics Inc. Completes Novel Commercially Enabling Progesterone Formulation for TBI.  // Biomedical Market Newsletter;5/15/2011, p118 

    The article focuses on a report by Encore Therapeutics Inc. regarding the completion of its proprietary phospholipids nanoemulsion formulation of progesterone (ETI-411) for traumatic brain injury (TBI). It mentions that ETI-411 was approved by the U.S. Food and Drug Administration (FDA) which...

  • What is Stroke?  // Stroke: Hope through Research (NINDS);May2010, p2 

    The article presents information related to stroke. It is noted that when the blood supply to part of the brain is suddenly interrupted, a stroke occurs. It is mentioned that the symptoms of a stroke are easy to spot although a stroke occurs in the unseen reaches of the brain. It is stated that...

  • Therapeutic effects of progesterone and its metabolites in traumatic brain injury may involve non-classical signaling mechanisms. Cooke, Paul S.; Manjunatha K. Nanjappa; Zhihui Yang; Kevin K. W. Wang // Frontiers in Neuroscience;Jun2013, Vol. 7, p1 

    Traumatic brain injury (TBI) is an important and costly medical problem for which no clinically proven treatment currently exists. Studies in rodents and humans have shown beneficial effects of progesterone (P4) on both mortality and functional outcomes following TBI. Neuroprotective effects of...

  • Progesterone Offers No Benefits in Traumatic Brain Injury. Slomski, Anita // JAMA: Journal of the American Medical Association;2/24/2015, Vol. 313 Issue 8, p786 

    The article reports that progesterone has no benefits in traumatic brain injury (TBI) based on the clinical trials Progesterone for TBI, Experimental Clinical Treatment (PROTECT III) and Study of a Neuroprotective Agent, Progesterone, in Severe Traumatic Brain Injury (SYNAPSE) as of February 2015.

  • Introduction.  // Stroke: Hope through Research (NINDS);May2010, p1 

    The article presents information related to the history of stroke treatment. It is noted that stroke has been described as the sudden onset of paralysis by Hippocrates, the father of medicine. It is mentioned that to feed and care for the patient until the attack ran its course was the only...

  • Ischemic Stroke.  // Stroke: Hope through Research (NINDS);May2010, p3 

    The article presents information related to ischemic stroke. It is stated that when an artery supplying the brain with blood becomes blocked, an ischemic stroke occurs. It is mentioned that the most common cause of artery blockage and brain infarction is the blood clots. It is noted that...

  • Limiting Stroke-Induced Damage by Targeting an Acid Channel. Benveniste, Morris; Dingledine, Raymond // New England Journal of Medicine;1/6/2005, Vol. 352 Issue 1, p85 

    Examines the clinical implications of research in mice which showed the ability to limit stroke-induced damage by targeting an acid channel. Explanation of why brain neurons or more susceptible to ischemic injury than other tissues; Description of a recent study which showed that the activation...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics